PMID: 6968019Jan 1, 1980Paper

Polyclonal B cell activation by cell wall preparations of gram-positive bacteria. In vitro responses of spleen cells obtained from Balb/c, nu/nu, nu/+, C3H/He, C3H/HeJ and hybrid (DBA/N x Balb/c)F1 mice

Microbiology and Immunology
T Saito-TakiS Kawata

Abstract

The effects of polyclonal B cell activation (PBA) of cell walls and their cell wall fractions obtained from several kinds of gram-positive bacteria were studied using the anti-sheep red blood cell (SRBC) or anti-trinitrophenylated (TNP) SRBC plaque forming cell (PFC) responses of cultured spleen cells from Balb/c, athymic nu/nu, their littermates (nu/+), C3H/He (LPS-responder), C3H/HeJ (LPS-nonresponder), (CBA/N x Balb/c) F1 male with an X-linked defect in B cell function and the F1 female mice. The cell walls of Staphylococcus epidermidis (ATCC 155), Lactobacillus plantarum (ATCC 8014), Micrococcus lysodeikticus (NCTC 2665), Mycobacterium rhodochrous (ATCC 184), Streptomyces gardneri (ATCC 23911) and Nocardia corynebacteriodes (ATCC 14898) had the ability to induce polyclonal B cell responses in the spleen cells of Balb/c, nu/nu, nu/+, C3H/He and C3H/HeJ mice. The cell wall fractions prepared by enzymatic digestion from the cell walls of S. epidermidis, S. gardneri or N. corynebacteriodes were also capable of inducing polyclonal B cell responses. The responses of spleen cells from (CBA/N x Balb/c) F1 male mice to these active preparations, except the cell walls of M. rhodochrous which possess this ability. The PBA-ability of s...Continue Reading

References

Sep 1, 1976·The Journal of Experimental Medicine·D C MorrisonD M Jacobs
May 1, 1979·Infection and Immunity·S NagaoS Kotani
Jul 1, 1979·Infection and Immunity·H TakadaK Yokogawa
Sep 1, 1976·The Journal of Experimental Medicine·B M Sultzer, G W Goodman
Jul 1, 1977·Proceedings of the Society for Experimental Biology and Medicine·S SpecterL Chedid
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Aug 19, 1974·Biochemical and Biophysical Research Communications·F EllouzE Lederer
Nov 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·M B Rittenberg, K L Pratt

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Citations

Apr 1, 1984·Medicinal Research Reviews·A Adam, E Lederer
Jul 1, 1984·European Journal of Immunology·M A BachD Levitt
Jan 1, 1980·Microbiology and Immunology·M NakanoS Masuda
Sep 28, 2007·Canadian Journal of Microbiology·Christian BleauLucie Lamontagne

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