Polycystic ovarian syndrome, insulin resistance and thickness of the endometrium

European Journal of Obstetrics, Gynecology, and Reproductive Biology
G IatrakisG Kourounis

Abstract

Disorders possibly associated with insulin resistance (IR) are hyperandrogenemia, hirsutism, irregular menstrual cycles, central obesity and polycystic ovarian syndrome (PCOS). It is known that PCOS is related to a high risk of endometrial hyperplasia after many years of estrogen stimulation from anovulation. The purpose of the study was to estimate the thickness of the endometrium in women with IR without a diagnosis of PCOS and in women with PCOS without IR. Three groups of women included in the study: 15 women diagnosed as IR without PCOS, 16 women diagnosed as PCOS without IR and 20 women used as controls matched for age and body mass index (BMI) with the previous patients. Thickness of the endometrium was estimated in all cases with a transvaginal ultrasound in three consecutive measures during a cycle. The mean thickness of the endometrium was statistically higher in the PCOS group (11.1mm), and in the IR group (9.6mm), compared with the control group (6.2mm) (F=13.1, p<0.001). It is concluded that both in women diagnosed as having insulin resistance without PCOS, and in women with PCOS without insulin resistance, the ultrasonographically estimated thickness of the endometrium is relatively high and a closer follow-up of ...Continue Reading

References

Jun 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·A AkinmokunK G Alberti
Aug 1, 1992·The Journal of Clinical Endocrinology and Metabolism·S ZimmermannL R Krakoff
Feb 1, 1985·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·C Sakamoto
Aug 26, 1998·The Journal of Clinical Endocrinology and Metabolism·R S LegroA Dunaif
Jan 24, 2002·Biology of Reproduction·K B C ApparaoBruce A Lessey
Jun 12, 2002·Fertility and Sterility·Fernando Ovalle, Ricardo Azziz
Jun 25, 2002·Human Reproduction Update·Robert A Wild
Jan 9, 2004·Fertility and Sterility·UNKNOWN Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group
Sep 24, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Roger HartStephen Franks

❮ Previous
Next ❯

Citations

Sep 9, 2011·International Journal of Pediatric Endocrinology·David H GellerUNKNOWN of the Drug and Therapeutics Committee of the Pediatric Endocrine Society
May 10, 2011·Fertility and Sterility·Betsy A McCormickMira Aubuchon
Nov 6, 2009·American Journal of Physical Anthropology·Kathryn B H Clancy
Aug 3, 2013·International Journal of Cancer. Journal International Du Cancer·Ashley S FelixLouise A Brinton
Feb 24, 2016·Rejuvenation Research·Min Jung LeeIk-Hyun Cho
Nov 7, 2012·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Michael Fanta
Jan 19, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Yuan-Mei LiaoKoni Chen
Apr 27, 2012·Reproductive Sciences·Kewei ShangYoufei Guan
May 10, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Suchada IndhavivadhanaChongdee Dangrat
Oct 20, 2012·Acta Radiologica·Henrik LeonhardtMikael Hellström
Mar 3, 2012·Clinical and Experimental Reproductive Medicine·Joon Cheol ParkJeong Ho Rhee
Jun 10, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Antônio H de França NetoJosé M Aldrighi
Mar 24, 2017·Human Reproduction·D H AbbottJ E Levine
Aug 10, 2017·Journal of Ovarian Research·Ricardo Santos SimõesEdmund C Baracat
Feb 23, 2021·International Journal of Endocrinology and Metabolism·Marzieh Saei Ghare NazFahimeh Ramezani Tehrani
Mar 9, 2021·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Xingming ZhongXiangcai Wei
Jul 13, 2007·Current Opinion in Obstetrics & Gynecology
Nov 17, 2007·Current Opinion in Obstetrics & Gynecology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.