PMID: 14104085Jan 1, 1964Paper

POLYELECTROLYTES AND THEIR BIOLOGICAL INTERACTIONS

Biophysical Journal
A KATCHALSKY

Abstract

Polyelectrolytes are water-soluble electrically charged polymers. Their properties are determined by the interplay of the electrical forces, the Brownian motion of the macromolecular chain, and intermolecular Van der Waals forces. Charged polyacids or polybases are stretched by the electrostatic forces, as evidenced by increase in solution viscosity, or by the stretching of polyelectrolyte gels. The electrical field of the polyions is neutralized by a dense atmosphere of counter-ions. The counter-ion attraction to the polyions is expressed by a reduction of the osmotic activity of the polyion-the osmotic pressure being only 15 to 20 per cent of the ideal in highly charged polyelectrolytes neutralized by monovalent counter-ions, and as low as 1 to 3 per cent of the ideal for polyvalent counter-ions. Since the ionic atmosphere is only slightly dependent on added low molecular salt, the osmotic pressure of polyelectrolyte salt mixtures is approximately equal to the sum of the osmotic pressure of polyelectrolyte and salt alone. Acidic and basic polyelectrolytes interact electrostatically with precipitation at the point of polymeric electroneutrality. At higher salt concentrations the interaction is inhibited by the screening of pol...Continue Reading

Citations

Dec 1, 1976·The American Journal of Anatomy·I Nir, D C Pease
Mar 1, 1974·The Anatomical Record·A Van Harreveld, J Trubatch
Jun 1, 1966·Biopolymers·W B Gratzer, P McPhie
Jan 1, 1972·Histochemie. Histochemistry. Histochimie·I Benedeczky, A D Smith
Sep 15, 1977·The Journal of Membrane Biology·L Y Huang, R A Spangler
Jun 1, 1971·The Journal of Membrane Biology·E Bartels
Jan 1, 1972·Archives of Biochemistry and Biophysics·K J Wiegers, G Koch
Dec 1, 1967·Archives of Oral Biology·G Silverman, I Kleinberg
Oct 1, 1967·Developmental Biology·L T Stableford
Dec 1, 1969·European Journal of Biochemistry·J A ForresterG Ruhenstroth-Bauer
Oct 15, 1975·European Journal of Biochemistry·W B Gratzer, G H Beaven
Jan 2, 1978·European Journal of Biochemistry·J Pitha
Nov 1, 1967·Biological Reviews of the Cambridge Philosophical Society·M B Mathews
Jun 1, 1974·The Journal of Clinical Investigation·F S Wright, J Schnermann
Jun 1, 1968·Quarterly Reviews of Biophysics·A Katchalsky, R Spangler
Feb 28, 1975·Annals of the New York Academy of Sciences·W R Adey
Jan 1, 1981·Progress in Histochemistry and Cytochemistry·J SchrévelM Monsigny
Jul 16, 2013·Journal of Biomedical Materials Research. Part a·Viness PillayValence M K Ndesendo
Feb 26, 2016·The Journal of Physical Chemistry. B·Mahdi Ghelichi, Michael H Eikerling
Jan 1, 1971·Journal of Theoretical Biology·C D Cone
Dec 30, 1972·Journal of Molecular Biology·I Matsubara, G F Elliott
Mar 1, 1975·Microvascular Research·G B Thurston
Sep 25, 2004·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Hiroyoshi InoueYoko Honda
Sep 1, 1969·Experimental Neurology·H H Wang, W R Adey
Nov 13, 1972·Brain Research·F O Schmitt, R B Livingston
Jan 1, 1969·Experimental Neurology·W R AdeyT J Tarby
Jun 1, 1971·Experimental Neurology·A Van HarreveldF I Khattab
May 20, 2009·Biophysical Journal·Johannes FelsRyszard Grygorczyk
Jan 8, 2015·Pflügers Archiv : European journal of physiology·Ryszard GrygorczykSergei N Orlov

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.