Polyhydroxyalkanoates: an overview

Bioresource Technology
C S K ReddyV C Kalia

Abstract

Polyhydroxyalkanoates have gained major importance due to their structural diversity and close analogy to plastics. These are gaining more and more importance world over. Different sources (natural isolates, recombinant bacteria, plants) and other methods are being investigated to exert more control over the quality, quantity and economics of poly(3-hydroxybutyrate) (PHB) production. Their biodegradability makes them extremely desirable substitutes for synthetic plastics. The PHB biosynthetic genes phbA, phbB and phbC are clustered and organized in one phbCAB operon. The PHB pathway is highly divergent in the bacterial genera with regard to orientation and clustering of genes involved. Inspite of this the enzymes display a high degree of sequence conservation. But how similar are the mechanisms of regulation of these divergent operons is as yet unknown. Structural studies will further improve our understanding of the mechanism of action of these enzymes and aid us in improving and selecting better candidates for increased production. Metabolic engineering thereafter promises to bring a feasible solution for the production of "green plastic".

References

Jan 1, 1995·Canadian Journal of Microbiology·G EgginkG N Huijberts
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·C NawrathC Somerville
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Feb 21, 1998·Nucleic Acids Research·E L SonnhammerR Durbin
May 24, 2011·Journal of Agricultural and Food Chemistry·M Pau BalaguerPilar Hernandez-Munoz

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Citations

Oct 27, 2006·Analytical and Bioanalytical Chemistry·N A Ngo Thi, D Naumann
Dec 22, 2007·Applied Microbiology and Biotechnology·Jorge QuillaguamánRajni Hatti-Kaul
Nov 13, 2008·Applied Microbiology and Biotechnology·Luisa S SerafimMaria A M Reis
Feb 14, 2009·Applied Microbiology and Biotechnology·Christos P PapaneophytouDimitrios A Kyriakidis
May 26, 2009·Applied Microbiology and Biotechnology·Héctor GuzmánJorge Quillaguamán
Dec 22, 2009·Applied Microbiology and Biotechnology·Jorge QuillaguamánRajni Hatti-Kaul
Nov 4, 2010·Applied Microbiology and Biotechnology·Hong-Hui WangGuo-Qiang Chen
Feb 1, 2011·Applied Microbiology and Biotechnology·Nyok-Sean LauKumar Sudesh
Apr 20, 2011·Applied Microbiology and Biotechnology·Aid AtlićGerhart Braunegg
Jan 12, 2013·Applied Microbiology and Biotechnology·Kianoush Khosravi-DaraniKenji Tanaka
Jun 9, 2006·Journal of Industrial Microbiology & Biotechnology·Thomas M KeenanStuart W Tanenbaum
Jan 15, 2008·Journal of Industrial Microbiology & Biotechnology·Vipin Chandra Kalia, Hemant J Purohit
Dec 5, 2008·Journal of Industrial Microbiology & Biotechnology·Akhilesh Kumar Singh, Nirupama Mallick
Feb 4, 2009·Journal of Industrial Microbiology & Biotechnology·S VigneswariA A Amirul
Oct 2, 2012·Indian Journal of Microbiology·Sanjay K S PatelVipin C Kalia
Jan 16, 2014·Indian Journal of Microbiology·Mamtesh SinghVipin C Kalia
Dec 11, 2003·Biotechnology Advances·H Salehizadeh, M C M Van Loosdrecht
Mar 4, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Pinkee PhukonRaju Khan
Jul 11, 2012·Environmental Science & Technology·Katherine H RostkowskiMichael D Lepech
Dec 12, 2012·Preparative Biochemistry & Biotechnology·Alper Akkaya, Nurdan Pazarlioglu
Mar 9, 2010·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Huizheng WangXiuguo Zhang
Apr 7, 2005·Applied and Environmental Microbiology·Patrick G WardKevin E O'Connor
Mar 31, 2012·Journal of Bacteriology·Laleh Parsa YeganehGhasem Hosseini Salekdeh
Apr 27, 2010·Journal of Bacteriology·J Cameron ThrashStephen J Giovannoni
Sep 22, 2009·Canadian Journal of Microbiology·Fernanda MatiasJoão Antonio Pêgas Henriques
Dec 22, 2005·Journal of Biomaterials Science. Polymer Edition·Suleyman CoskunVasif Hasirci
Jul 22, 2009·Microbial Cell Factories·Mamtesh SinghVipin C Kalia
Sep 13, 2011·AMB Express·Anastasia A PantazakiDimitra A Lambropoulou
Nov 30, 2013·Applied Microbiology and Biotechnology·Lucia Salamanca-CardonaChristopher T Nomura
May 20, 2014·Bioresource Technology·Pearl PassanhaSandra R Esteves
Oct 1, 2013·Bioprocess and Biosystems Engineering·Abeed Fatima Mohidin BatchaHamidah Abdullah

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