Oct 1, 1975

Polymer concentration dependence of the helix to random coil transition of a charged polypeptide in aqueous salt solution

Biophysical Chemistry
K Nitta, M Yoneyama

Abstract

The helix to coil transition of poly(L-glutamic acid) was investigated in 0.05 and 0.005 M aqueous potassium chloride solutions by use of potentiometric titration and circular dichroism measurement. Polymer concentration dependence of the transition was observed in the range from 0.006 to 0.04 monomol/e in 0.005 M KG1 solution. The polymer concentration dependence can be interpreted by current theories of the transition of charged polypeptides and of titration curves of linear weak polyelectrolytes taking the effect of polymer concentration into consideration.

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Citations

Mentioned in this Paper

Thermodynamics
Molecular Helix
Poly(gamma-glutamic acid)
Helix (Snails)
Ions
Slow-K
Polymers
Protein Conformation
Solutions
Polypeptides

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