Polymeric nanoparticles for enhancing antiretroviral drug therapy

Drug Delivery
Thirumala GovenderIrene Mackraj

Abstract

There is a surge of interest internationally in the study of nanoparticles for enhancing antiretroviral (ARV) drug therapy. This paper presents a comprehensive review on polymeric nanoparticles for ARV drug therapy. Their main applications for targeting to macrophages and the brain, as well as other studies on modifications to enhance drug loading, decrease toxicity, and also to increase drug absorption are reviewed. The physicochemical characterization properties and their in vitro/in vivo performances are summarized. Further studies that need to be undertaken for formulation optimization are also identified. This review highlights the significant potential that nanoparticles have for the future effective treatment of HIV/AIDS patients on ARV drug therapy.

References

May 1, 1992·Chemical & Pharmaceutical Bulletin·T KawaguchiM Saneyoshi
Jan 1, 1985·Annual Review of Immunology·H C Lane, A S Fauci
May 1, 1994·Research in Virology·A BenderH von Briesen
Aug 1, 1994·Biological & Pharmaceutical Bulletin·T SekiK Juni
Jan 7, 1998·Immunological Reviews·O J CohenA S Fauci
Aug 1, 1998·Journal of Controlled Release : Official Journal of the Controlled Release Society·R LöbenbergJ Kreuter
Aug 5, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·F De JaeghereR Gurny
Nov 1, 2001·Journal of Exposure Analysis and Environmental Epidemiology·R A JenkinsR H Ilgner
Nov 24, 2001·International Journal of Pharmaceutics·Jun XiangXiaoling Li
Jan 10, 2002·Biochimica Et Biophysica Acta·Jean-François GagnéMichel G Bergeron
Feb 13, 2002·International Journal of Pharmaceutics·Carla Sánchez-LafuentePaola Mura
Mar 1, 2002·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·S Lucas
Mar 12, 2003·Advanced Drug Delivery Reviews·Jayanth Panyam, Vinod Labhasetwar
Nov 26, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·C VauthierP Couvreur
May 8, 2004·International Journal of Pharmaceutics·D GopinathD Rambhau
Sep 8, 2004·Advanced Drug Delivery Reviews·Lisa Brannon-Peppas, James O Blanchette
Jan 18, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sunil T K Narishetty, Ramesh Panchagnula
Mar 7, 2006·Current Pharmaceutical Design·R C RathbunJ R Stephens
Mar 16, 2006·The Journal of Pharmacy and Pharmacology·S P VyasSanyog Jain
Sep 5, 2006·Expert Opinion on Drug Delivery·Tushar K VyasMansoor M Amiji
Sep 14, 2006·Pharmaceutical Research·Lipa K Shah, Mansoor M Amiji
Nov 10, 2006·Advanced Drug Delivery Reviews·Vladimir P Torchilin
Mar 17, 2007·Journal of Drug Targeting·José M LanaoClara I Colino
May 4, 2007·International Journal of Clinical Pharmacology and Therapeutics·S DelliauxY Jammes
May 29, 2007·Advanced Drug Delivery Reviews·Ho Lun WongXiao Yu Wu
May 29, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kinam Park

❮ Previous
Next ❯

Citations

Aug 24, 2013·International Journal of Nanomedicine·Sidi YangEmmanuel A Ho
Feb 23, 2011·Marine Drugs·Thanh-Sang Vo, Se-Kwon Kim
May 14, 2009·Expert Opinion on Drug Delivery·Eugen BarbuDariusz C Górecki
Dec 30, 2014·Journal of Pharmaceutical Sciences·Rahul S KalhapureThirumala Govender
Aug 24, 2010·International Journal of Pharmaceutics·R ShegokarR H Müller
Jan 2, 2010·Neurobiology of Disease·Stephanie D Kraft-TerryHoward E Gendelman
Nov 17, 2009·Advanced Drug Delivery Reviews·Ho Lun WongReina Bendayan
Nov 17, 2009·Advanced Drug Delivery Reviews·José das NevesBruno Sarmento
Oct 12, 2011·International Journal of Pharmaceutics·Ranjita Shegokar, Kamalinder K Singh
Jul 21, 2010·Nanoscale·Daniel R Cooper, Jay L Nadeau
Dec 3, 2009·Chemical & Pharmaceutical Bulletin·Davood HasanzadehShirzad Azarmi
Apr 19, 2011·Journal of the American Animal Hospital Association·Jennifer L McCown, Andrew J Specht
Sep 5, 2017·Journal of Drug Targeting·Nila Mary VargheseShailendra K Saxena
Oct 8, 2018·Systematic Reviews·Trust SaidiTania S Douglas
May 14, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abuzer Alp YetisginOzlem Kutlu
May 17, 2012·Viruses·Raveen ParboosingHendrik G Kruger
Jun 30, 2019·Current Drug Discovery Technologies·Victor B Oti
May 2, 2021·Microbial Pathogenesis·Muthupandian SaravananHamed Barabadi
Feb 18, 2020·Nanomedicine : Nanotechnology, Biology, and Medicine·Ajay SinghParas N Prasad

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V
Elizabeth OjewoleThirumala Govender
© 2022 Meta ULC. All rights reserved