Polymeric nanoparticles from rapid expansion of supercritical fluid solution

Chemistry : a European Journal
Ya-Ping SunLiangwei Qu

Abstract

In this concept paper we highlight applications of supercritical fluid technology in particle formation and production, especially some recent advances in the rapid expansion of supercritical solutions (RESS) processing technique. We also highlight the simple but significant modification to the traditional RESS by using a liquid solvent or solution at the receiving end of the supercritical solution expansion, or the rapid expansion of a supercritical solution into a liquid solvent (RESOLV), and applications of the technique to the preparation of nanoparticles. In particular, successes and challenges in the use of RESOLV for nanoscale (<100 nm) polymeric particles and the subsequent protection of the suspended nanoparticles from agglomeration are discussed.

References

Dec 1, 1994·Journal of Pharmaceutical Sciences·S D YeoT M Przybycien
Jun 1, 1996·Journal of Pharmaceutical Sciences·M A WintersS J Prestrelski
Aug 1, 1997·Journal of Pharmaceutical Sciences·B SubramaniamK Snavely
Aug 5, 1998·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·J Thies, B W Müller
Mar 27, 2001·Accounts of Chemical Research·G ZhangC Wu
Oct 24, 2001·The Journal of Organic Chemistry·Christopher E. BunkerYa-Ping Sun
Oct 31, 2002·Angewandte Chemie·Dieter Horn, Jens Rieger
Jun 26, 2003·Journal of the American Chemical Society·Mohammed J Meziani, Ya-Ping Sun
Feb 3, 2004·Angewandte Chemie·Mohammed J MezianiYa-Ping Sun
Feb 5, 1993·Biotechnology and Bioengineering·S D YeoH Bernstein
Jun 1, 1986·Biotechnology Progress·K A Larson, M L King

❮ Previous
Next ❯

Citations

May 31, 2008·Nanomedicine·Federica ChielliniEmo Chiellini
May 11, 2007·Expert Opinion on Drug Delivery·Mayank D Bhavsar, Mansoor M Amiji
Sep 1, 2015·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Brittany L BanikJustin L Brown
May 7, 2011·Journal of Microencapsulation·Pegi Ahlin Grabnar, Julijana Kristl
Jul 23, 2014·AAPS PharmSciTech·Rishi PaliwalSrinath Palakurthi
Nov 22, 2005·Expert Opinion on Drug Delivery·Pankaj PathakYa-Ping Sun
Apr 11, 2017·Kona : Powder Science and Technology in Japan·Susanne R Youngren-OrtizMahavir B Chougule
Jan 31, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Mary Cano-SarabiaJaume Veciana
Jan 25, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Pankaj PathakYa-Ping Sun
Sep 17, 2021·International Journal of Pharmaceutics·Rahul KumarPranava Chaudhari

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.