Polymicrobial bloodstream infections among children and adolescents with central venous catheters evaluated in ambulatory care

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Kevin J DownesSamir S Shah

Abstract

Bloodstream infections (BSIs) are an ever-present concern for clinicians evaluating ill-appearing pediatric patients with central venous catheters (CVCs) in the ambulatory care setting. We performed a case-control study of a cohort of 200 pediatric patients who were evaluated in the ambulatory care setting and who were found to have laboratory-confirmed BSI in the context of a CVC. This study sought to compare patients with polymicrobial versus monomicrobial BSIs to identify potential risk factors for polymicrobial BSI. Of the 200 patients enrolled in the study, 73 (37%) had a polymicrobial BSI. Patients with polymicrobial BSI were more likely than those with monomicrobial BSI to be younger (P=.002) and less likely to have been recently discharged from the hospital (P=.01). The odds of a polymicrobial BSI were >4 times greater for patients aged <3 years than for those aged >or=3 years (odds ratio, 4.54; 95% confidence interval, 1.68-12.29), and the odds were 50% lower for those discharged from the hospital in the prior 7 days than for those without recent hospitalization (odds ratio, 0.46; 95% confidence interval, 0.22-0.95) after controlling for an underlying cancer diagnosis and the time of year during which a patient present...Continue Reading

References

Sep 7, 1979·JAMA : the Journal of the American Medical Association·D KianiT R Neblett
Jul 1, 1992·Journal of Pediatric Surgery·M P La QuagliaJ S Groeger
Nov 1, 1988·American Journal of Diseases of Children·W A Bonadio
Sep 1, 1986·Diagnostic Microbiology and Infectious Disease·M P WeinsteinJ R Murphy
Nov 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D PittetR P Wenzel
Feb 1, 1993·Annals of Internal Medicine·J ConcatoT R Holford
Jun 19, 1998·Journal of the American College of Surgeons·D B ShaulW H Mason
Apr 17, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L A MermelUNKNOWN Society for Healthcare Epidemiology of America
Jun 8, 2001·American Journal of Infection Control·B H StoverUNKNOWN Pediatric Prevention Network
Mar 15, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Samir S ShahLouis M Bell
May 25, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Theresa L SmithWilliam R Jarvis
Oct 25, 2002·Journal of Vascular and Interventional Radiology : JVIR·Nancy MoureauCharles P Semba
Aug 13, 2003·The Pediatric Infectious Disease Journal·Hilmar WisplinghoffMichael B Edmond
Mar 17, 2004·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J R Wilson, A P Limaye
Apr 29, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Rogier C J de JongeReinoud J B J Gemke
Feb 3, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M NørgaardH T Sørensen
Aug 10, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ali Mirza OnderGaston Zilleruelo
Dec 8, 2006·Journal of Tropical Pediatrics·K S LakshmiP Ray
Jan 2, 2007·Journal of Clinical Gastroenterology·Alexandre R MarraDonald F Kirby
Jan 20, 2007·Intensive Care Medicine·M Angeles García-TeresaUNKNOWN Spanish Central Venous Catheter Pediatric Study Group
Jun 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kenneth V I RolstonAmar Safdar

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Citations

Jun 5, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V CecinatiS Esposito
Mar 29, 2013·The Journal of Antimicrobial Chemotherapy·Emilio BouzaMarta Rodríguez-Créixems
Mar 14, 2012·The Journal of Infection·Seong Yeon ParkYang Soo Kim
Sep 28, 2010·Journal of Infection and Public Health·Raphaelle GirardBertrand Coiffier
Jul 25, 2013·Pediatric Blood & Cancer·Michael L RinkeMarlene R Miller
Nov 3, 2010·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jiun-Nong LinHsi-Hsun Lin
Aug 20, 2016·Annals of Clinical Microbiology and Antimicrobials·Noah Obeng-NkrumahGeorgina Awuah-Mensah
Apr 15, 2017·Pediatric Blood & Cancer·Ramia ZakhourIssam Raad
Mar 31, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Petra WiersmaArjun Srinivasan
Jun 25, 2014·Antimicrobial Agents and Chemotherapy·Mohamed A JamalIssam I Raad
Nov 17, 2017·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sunil Kumar Garg, Pragya Garg
Apr 30, 2014·The Pediatric Infectious Disease Journal·Michael A PadulaMary C Harris
Nov 22, 2017·Turkish Journal of Medical Sciences·Rana İşgüderHasan Ağın
Dec 29, 2020·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Mohammed S AlmuhayawiVolkan Özenci

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