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Polymorphism analyses and protein modelling inform on functional specialization of Piwi clade genes in the arboviral vector Aedes albopictus

PLoS Neglected Tropical Diseases

Dec 4, 2019

Michele MarconciniMariangela Bonizzoni

Abstract

Current knowledge of the piRNA pathway is based mainly on studies on Drosophila melanogaster where three proteins of the Piwi subclade of the Argonaute family interact with PIWI-interacting RNAs to silence transposable elements in gonadal tissues. In mosquito species that transmit epide...read more

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Surface
Homology Modeling
Transcript
Opposite
Biochemical Pathway
Species
Culicidae
Piwi-Interacting RNA
Antiviral Agents
Arboviruses
5
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Polymorphism analyses and protein modelling inform on functional specialization of Piwi clade genes in the arboviral vector Aedes albopictus

PLoS Neglected Tropical Diseases

Dec 4, 2019

Michele MarconciniMariangela Bonizzoni

PMID: 31790401

DOI: 10.1371/journal.pntd.0007919

Abstract

Current knowledge of the piRNA pathway is based mainly on studies on Drosophila melanogaster where three proteins of the Piwi subclade of the Argonaute family interact with PIWI-interacting RNAs to silence transposable elements in gonadal tissues. In mosquito species that transmit epide...read more

Mentioned in this Paper

Surface
Homology Modeling
Transcript
Opposite
Biochemical Pathway
Species
Culicidae
Piwi-Interacting RNA
Antiviral Agents
Arboviruses
5

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