PMID: 9531648May 23, 1998Paper

Polymorphism analysis of 4 loci of X-chromosome in a Chinese population of the Han nationality

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
X DouY Gong

Abstract

To investigate the polymorphism of 4 loci of X-chromosome in the Hans. Using PCR-SSLP, the authors analysed the polymorphism of DXS1068, DXS7132, DXS6804 and DXS6799 in the X-chromosome in 70 randomly selected female Hans. The number of alleles in the 4 loci were 5,5,5 and 6 respectively; there were no significant differences between the observed and estimated and genotype probabilities of the 4 loci; the estimates of heterozygosity of 4 loci were 0.6819, 0.6895, 0.7659 and 0.6483 respectively and there were no significant differences between the observed and estimated heterozygosity of the 4 loci. The distribution of alleles and genotype probabilities of 4 loci all observe the Hardy-Weinberg equilibrium.

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