PMID: 6170484Jul 1, 1981Paper

Polymorphism in chromosome 4

Clinical Genetics
S BardhanK Davis

Abstract

Chromosomal analyses were performed on 302 individuals, using QFQ banding techniques to determine the occurrence of heteromorphism of chromosome 4. Two type of heteromorphism were observed, one showing an intensely fluorescent band in the centromere region and the other an intensely fluorescent band in the proximal area of the short arm. No one individual possessed both type of heteromorphism. A higher frequency of chromosome 4 heteromorphism was found in patients with schizophrenia, mental retardation, hyperactivity, developmental delay and speech impediments than in normal individuals.

References

Mar 1, 1979·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·R S Verma, H Dosik
Jul 1, 1976·Annals of Human Genetics·K E BucktonH J Evans
Jan 1, 1975·Cytogenetics and Cell Genetics·W H McKenzie, H A Lubs
Jan 1, 1980·International Review of Cytology·R S Verma, H Dosik

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Citations

Jan 1, 1982·Human Genetics·I HansmannT Grimm

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