PMID: 16649669May 3, 2006Paper

Polymorphism of dental formula and segregation of its variants in a pedigree of kerry blue terrier dogs

Genetika
T I AksenovichP M Borodin

Abstract

Polymorphism of the dental formula was analyzed in a sophisticated pedigree of Kerry Blue Terrier. A lack of one or more lower premolars was observed in some dogs. Two different patterns of missing teeth were identified. One pattern consisted in agenesis of a second premolar, often in combination with agenesis of neighbor teeth, including the fourth premolar. In the second pattern, agenesis of a fourth premolar was expressed as an isolated abnormality. It was shown previously that the first pattern is inherited as a recessive trait with near complete penetrance. In this work, the control of a major-gene was demonstrated for the second pattern. This abnormality develops in 70-80% of mutant homozygotes and in no more than 20% of heterozygotes and wild-type homozygotes. It was shown that the two dentition abnormalities are controlled by different genes, which were designated LPA2 and LPA4 (Lower Premolar Agenesis).

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Citations

Oct 9, 2007·Archives of Oral Biology·Asuka NatsumeHajime Hanamura
Mar 3, 2007·Archives of Oral Biology·Takamichi JogaharaHajime Hanamura
May 3, 2006·Genetika·I V ZorkaltsevaT I Aksenovich

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