Polymorphism of the PE domain of PE/PE_PGRS sequences in clinical isolates of Mycobacterium bovis in Mexico

Veterinary Microbiology
Marco Antonio Santillan-FloresClara Espitia

Abstract

Polymorphism of the PE domain of PE/PE_PGRS sequences was studied in Mycobacterium bovis isolates from different Mexican states. Samples were analyzed by spolygotyping and RFLP using IS6110 and a 235-bp fragment of the PE domain of PE/PE_PGRS as probes. With the PE probe, three different genotypes were observed, one being predominant in all states. These results confirm the high conservation of the PE domain and suggests a potential role for PE sequence as a stable genetic marker for bovine tuberculosis.

Citations

Jun 19, 2012·Preventive Veterinary Medicine·José A Gutiérrez ReyesFeliciano Milián Suazo
Jun 6, 2008·Preventive Veterinary Medicine·Feliciano Milian-SuazoJanet B Payeur
Apr 20, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Timothy C RodwellRichard S Garfein
Aug 24, 2018·PloS One·Claudia Angélica Perea RazoGerminal Jorge Cantó Alarcón
Oct 23, 2019·Veterinary Sciences·Alejandro Benítez-GuzmánJosé A Gutiérrez-Pabello

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