Polymorphisms and haplotypes in candidate genes related to angiogenesis and endothelial dysfunction in preeclampsia.

Journal of Pregnancy
M R LuizonV C Sandrim

Abstract

Valenzuela and colleagues have recently reviewed some polymorphisms in important candidate genes involved in different pathogenic mechanisms related to preeclampsia (PE) and concluded that various studies in different populations have identified maternal polymorphisms associated with PE. However, we would like to contribute to some studies regarding candidate genes related to angiogenesis and endothelial dysfunction in PE performed in the Brazilian population. Specifically, genotypes and haplotypes formed by polymorphisms of VEGF, eNOS and MMP-9, along with an example of the interaction among these genes in the prediction of PE. Our suggestions may provide additional information with clinical relevance to PE susceptibility.

References

Oct 16, 2008·Pharmacogenomics·Valeria C SandrimJose E Tanus-Santos
Mar 10, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Ana C T PaleiJose E Tanus-Santos
May 12, 2010·Molecular Human Reproduction·Valeria C SandrimJose E Tanus-Santos
Feb 22, 2011·Best Practice & Research. Clinical Obstetrics & Gynaecology·Jennifer A HutcheonK S Joseph
Mar 10, 2011·Clinical Biochemistry·Marcelo Rizzatti Luizon, Valeria Cristina Sandrim
Dec 17, 2011·Journal of Pregnancy·Francisco J ValenzuelaSebastián E Illanes
May 11, 2012·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Marcelo R LuizonJose E Tanus-Santos

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Citations

Jan 10, 2019·BMC Pregnancy and Childbirth·Melissa D AmoscoCynthia P Palmes-Saloma
Apr 30, 2021·Colombia médica : CM·José Pacheco-RomeroAndrea Naranjo

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