Polymorphisms at fifteen tetrameric short tandem repeat loci in three ethnic populations of Bengal, India

Legal Medicine
Anamika SinghV K Kashyap

Abstract

The study presents allele frequency data at 15 tetrameric short tandem repeat (STR) loci (D3S1358, THO1, D21S11, D18S51, D5S818, D13S317, D7S820, D16S539, CSF1PO, vWA, D8S1179, TPOX, D2S1338, D19S433 and FGA) in three ethnic populations--Mahishya, Bauri and Namasudra of Bengal to evaluate their utility in Forensic testing and understanding population structure and dynamics. A total of 169 individuals were studied from the selected populations. On an average the combined power of discrimination and power of exclusion in these groups was found 0.97 and 0.99, respectively. The allele distribution pattern shows possible genetic admixture between these ethnic groups which could be attributed to their close geographical proximity and occupying almost similar position in the social hierarchy. This study suggests that the 13 Combined DNA Index System (CODIS) markers and two added markers named D2S1338, D19S433 are highly informative and therefore suitable in matching biological specimen in human identification and population genetic study.

References

Mar 1, 1987·Annals of Human Biology·R ChakrabortyM Roy
Feb 1, 1974·Genetics·M Nei, A K Roychoudhury
Apr 20, 2000·Indian Journal of Pediatrics·M Singh
Aug 14, 2002·Forensic Science International : Synergy·R TrivediV K Kashyap
Nov 13, 2002·Forensic Science International : Synergy·R Ashma, V K Kashyap
Dec 13, 2002·Forensic Science International : Synergy·Sanghamitra Sahoo, V K Kashyap

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