PMID: 8608683Nov 1, 1995Paper

Polymyalgia rheumatica and temporal arteritis: a retrospective study of 111 patients

Clinical Rheumatology
J C MertensB A Dijkmans

Abstract

There is no unanimity as to whether polymyalgia rheumatica (PMR) and temporal arteritis (TA) are two distinct diseases or different features of one disease. The objective of this study was to assess the value of histological findings of temporal artery biopsy and the efficacy and complications of drug therapy as well as the frequency of malignancies. It was carried out as a retrospective follow-up study. One hundred eleven patients (89 PMR, 14 TA and 8 PMR+TA) were studied. In 56 patients with PMR a temporal artery biopsy was performed; in none of these biopsies was active arteritis found. Of the 19 patients with TA or PMR+TA, where a temporal artery biopsy was performed, arteritis was found in 15 patients. Reactivation occurred in 27 patients: 4 patients using NSAIDs and 23 patients using corticosteroids. Side effect of the medication included vertebral compression in 10 patients, most of whom were using corticosteroids. Malignancies were diagnosed in 12 of the 111 patients. Most malignancies were diagnosed long before or after the diagnosis of PMR. In case of a PMR diagnosed by the clinician a biopsy of the temporal artery has no value, while the yield of this diagnostic procedure is high in TA. Reactivation was seen quite of...Continue Reading

References

Oct 1, 1979·Annals of the Rheumatic Diseases·H A BirdP H Wood
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Citations

Mar 18, 2003·Joint, Bone, Spine : Revue Du Rhumatisme·Javier NarváezD Roig-Escofet
Dec 24, 2002·Current Opinion in Rheumatology·Eliza Chakravarty, Mark C Genovese
Sep 16, 2005·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Andrew W Nichols
Jan 12, 2000·Australian and New Zealand Journal of Medicine·P A Gatenby
Nov 26, 2010·Annals of the Rheumatic Diseases·Christian DejacoUNKNOWN International Work Group for PMR and GCA
Jul 17, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·P M Moore, B Richardson
Feb 3, 2016·Internal Medicine·Hiroko TsunemineTakayuki Takahashi
Mar 5, 2013·Seminars in Arthritis and Rheumatism·Hubert de BoyssonBoris Bienvenu
Apr 28, 2018·BMC Evolutionary Biology·Kim-Kee TanSazaly AbuBakar
Jan 9, 2019·Clinical Rheumatology·S DeshayesUNKNOWN French Study Group for Large Vessel Vasculitis (GEFA)

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