Poly(N-acryloyl glycinamide): a fascinating polymer that exhibits a range of properties from UCST to high-strength hydrogels

Chemical Communications : Chem Comm
Ziyang Xu, Wenguang Liu

Abstract

It has been fifty-four years since the N-acryloyl glycinamide (NAGA) monomer and its polymer (PNAGA) were first reported (in 1964). Over the past decades, PNAGA aqueous solution systems within a broad concentration range have been prepared and significantly distinct performances have been observed. This feature article is aimed toward introducing the representative properties (aggregation, UCST-type phase separation, the thermoreversible sol ⇔ gel transition behaviors and the high mechanical properties) of PNAGA aqueous systems with three concentration regions (low, medium and high concentration). In particular, the fabrication of dual-amide hydrogen bonding reinforced high-strength supramolecular polymer hydrogels and the relevant biomedical applications are highlighted. The potential challenges, as well as the future prospects of the PNAGAs, are also indicated.

References

Sep 6, 2003·International Journal of Biological Macromolecules·Edith van den Bosch, Constant Gielens
Apr 8, 2004·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Marco ArnoldJoachim P Spatz
May 21, 2010·Chemical Communications : Chem Comm·Stefan GlatzelJean-François Lutz
Nov 12, 2013·Journal of Controlled Release : Official Journal of the Controlled Release Society·Mahfoud BousttaMichel Vert
Dec 20, 2014·Biomaterials·Mark D SwartzlanderStephanie J Bryant
Dec 19, 2013·The Journal of Physical Chemistry Letters·Pavel Jungwirth
Mar 9, 2017·Macromolecular Rapid Communications·Hongbo WangWenguang Liu
Jul 19, 2017·Macromolecular Rapid Communications·Hui GuoNicolas Sanson
Jul 7, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xuan XueCameron Alexander

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Citations

Feb 23, 2020·Macromolecular Rapid Communications·Tomoyuki KogaNobuyuki Higashi
Mar 19, 2020·Macromolecular Rapid Communications·Pattida LertturongchaiKhalid Ferji
Sep 5, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Wei HuZaizai Tong
Jan 16, 2021·Macromolecular Rapid Communications·Jingcong Xu, Volker Abetz
Feb 18, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Dong YangSami Hietala
Mar 11, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Nobuyuki Morimoto, Masaya Yamamoto
Apr 3, 2021·International Journal of Pharmaceutics·Kangkang LiXuehong Chen
Jul 31, 2021·Journal of Biomaterials Science. Polymer Edition·Samuel Ogbeide Ebhodaghe
Feb 9, 2021·Chemistry of Materials : a Publication of the American Chemical Society·Soyon Kim, Min Lee
Nov 25, 2020·ACS Applied Materials & Interfaces·Jian LiPingchuan Sun
Sep 4, 2021·Beilstein Journal of Organic Chemistry·Patricia FlemmingPetra Uhlmann
Oct 2, 2021·Chembiochem : a European Journal of Chemical Biology·Katrin KappaufChristiane Claaßen
Nov 9, 2021·Chemical Reviews·Zhiwei LiYadong Yin

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Methods Mentioned

BETA
static light scattering
column chromatography
electrophoresis
atomic force microscopy
differential scanning calorimetry
by
rheology
biosensors

Software Mentioned

PNAGA

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