Poly(N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications

Biomaterials
Kenichi NagaseT Okano

Abstract

Thermoresponsive surfaces, prepared by grafting of poly(N-isopropylacrylamide) (PIPAAm) or its copolymers, have been investigated for biomedical applications. Thermoresponsive cell culture dishes that show controlled cell adhesion and detachment following external temperature changes, represent a promising application of thermoresponsive surfaces. These dishes can be used to fabricate cell sheets, which are currently used as effective therapies for patients. Thermoresponsive microcarriers for large-scale cell cultivation have also been developed by taking advantage of the thermally modulated cell adhesion and detachment properties of thermoresponsive surfaces. Furthermore, thermoresponsive bioseparation systems using thermoresponsive surfaces for separating and purifying pharmaceutical proteins and therapeutic cells have been developed, with the separation systems able to maintain their activity and biological potency throughout the procedure. These applications of thermoresponsive surfaces have been improved with progress in preparation techniques of thermoresponsive surfaces, such as polymerization methods, and surface modification techniques. In the present review, the various types of PIPAAm-based thermoresponsive surfaces ...Continue Reading

References

Sep 1, 1990·Bio/technology·T TakezawaK Yoshizato
Jan 1, 1993·Biomaterials·G RollasonM V Sefton
May 23, 1998·Journal of Biomedical Materials Research·H A von RecumT Okano
Dec 22, 1998·Journal of Biomaterials Science. Polymer Edition·H von RecumS W Kim
Oct 16, 1999·Journal of Controlled Release : Official Journal of the Controlled Release Society·J E ChungT Okano
Jan 25, 2000·Journal of Biomedical Materials Research·O H KwonT Okano
Feb 19, 2000·Journal of Biomaterials Science. Polymer Edition·T AoyagiT Okano
Oct 6, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·M KurisawaT Okano
Dec 26, 2001·Chemical Reviews·K Matyjaszewski, J Xia
Jan 5, 2002·Advanced Drug Delivery Reviews·Akihiko Kikuchi, Teruo Okano
Feb 9, 2002·Journal of Biomedical Materials Research·Tatsuya ShimizuTeruo Okano
Aug 9, 2002·Journal of the American Chemical Society·Tao WuJan Genzer
Apr 18, 2003·Biomaterials·Tatsuya ShimizuTeruo Okano
Apr 23, 2003·Analytical Chemistry·Hidenori YamanakaTeruo Okano
Feb 26, 2004·Journal of Controlled Release : Official Journal of the Controlled Release Society·Naoya TakedaTeruo Okano
Sep 17, 2004·The New England Journal of Medicine·Kohji NishidaYasuo Tano
Mar 4, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Takeshi Mori, Mizuo Maeda
Jul 1, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Yoshikatsu AkiyamaTeruo Okano
Nov 1, 2005·The Journal of Thoracic and Cardiovascular Surgery·Imran A MemonHikaru Matsuda
Jan 26, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T YokoyamaY Nakajima
Jan 28, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Tatsuya ShimizuTeruo Okano
Feb 14, 2006·Biomacromolecules·Tomohiro MaedaTakao Aoyagi

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Citations

Jan 31, 2018·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Hirotaka SugaAkihiko Takushima
Jul 17, 2018·Journal of Drug Targeting·Daniel Cristian Ferreira SoaresMarli Luiza Tebaldi
Jan 24, 2019·International Journal of Molecular Sciences·Kenichi NagaseHideko Kanazawa
Aug 31, 2019·Biotechnology Journal·Zheng LuoXian Jun Loh
Jan 16, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Sonia LanzalacoElaine Armelin
Jan 16, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Falko DoberenzThomas Groth
Jan 22, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Eiji Yuba
Feb 29, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Keiichi ImatoNaoya Takeda
Mar 19, 2020·Tissue Engineering. Part C, Methods·Takeshi HoriHiroo Iwata
Jun 24, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kenichi NagaseTeruo Okano
Aug 4, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Tong ShuMichael J Serpe
Mar 21, 2020·Advanced Science·Shida MiaoLijie Grace Zhang
Aug 19, 2020·Macromolecular Rapid Communications·Kenichi NagaseHideko Kanazawa
Jul 25, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Weiwei SunAiqin Luo
Nov 7, 2019·Macromolecular Rapid Communications·Tomomi KonishiSeimei Shiratori
Dec 19, 2017·Journal of Biomaterials Applications·Zhi LiZhenzhong Zhang
Jun 6, 2018·International Journal of Molecular Sciences·Minami MatsuuraHideko Kanazawa
Sep 15, 2018·Chemical Communications : Chem Comm·Seigo SuzukiTakeshi Serizawa
Apr 5, 2019·Nature Biomedical Engineering·James Q YinJames A Ankrum
Jul 30, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Alejandra Patino-GuerreroMehdi Nikkhah
May 14, 2020·Gels·Esfandyar AskariMohsen Akbari
Oct 20, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Hao GengChengfen Xing
Nov 5, 2020·Macromolecular Bioscience·Silvia BrunatoPaolo Caliceti
Jan 20, 2021·Macromolecular Bioscience·Arvind K Singh ChandelTaichi Ito
Nov 10, 2020·Analytica Chimica Acta·Kenichi Nagase, Hideko Kanazawa
Jan 26, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Krishan KumarPannuru Venkatesu
Oct 8, 2020·Materials Today. Bio·Jingwen SongKatsuhiko Ariga
Feb 14, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Matthew WalkerMarco Cantini
Feb 19, 2021·ACS Biomaterials Science & Engineering·Kuan Un WongGiselle C Yeo
Feb 20, 2021·International Journal of Biological Macromolecules·Fuyu SongHaisong Wang

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