Polypharmacy and psychotropic drug loading in patients with schizophrenia in Asian countries: Fourth survey of Research on Asian Prescription Patterns on antipsychotics

Psychiatry and Clinical Neurosciences
Shu-Yu YangShih-Ku Lin

Abstract

The aim of the present study was to survey the prevalence of antipsychotic polypharmacy and combined medication use across 15 Asian countries and areas in 2016. By using the results from the fourth survey of Research on Asian Prescription Patterns on antipsychotics, the rates of polypharmacy and combined medication use in each country were analyzed. Daily medications prescribed for the treatment of inpatients or outpatients with schizophrenia, including antipsychotics, mood stabilizers, anxiolytics, hypnotics, and antiparkinson agents, were collected. Fifteen countries from Asia participated in this study. A total of 3744 patients' prescription forms were examined. The prescription patterns differed across these Asian countries, with the highest rate of polypharmacy noted in Vietnam (59.1%) and the lowest in Myanmar (22.0%). Furthermore, the combined use of other medications, expressed as highest and lowest rate, respectively, was as follows: mood stabilizers, China (35.0%) and Bangladesh (1.0%); antidepressants, South Korea (36.6%) and Bangladesh (0%); anxiolytics, Pakistan (55.7%) and Myanmar (8.5%); hypnotics, Japan (61.1%) and, equally, Myanmar (0%) and Sri Lanka (0%); and antiparkinson agents, Bangladesh (87.9%) and Vietna...Continue Reading

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Citations

Dec 24, 2019·The International Journal of Neuropsychopharmacology·Shih-Ku Lin
Jul 17, 2020·Neuropsychopharmacology Reports·Norio Yasui-Furukori, Kazutaka Shimoda
Dec 31, 2019·Community Mental Health Journal·Samer HammoudehHassen Al-Amin
Jun 13, 2020·Frontiers in Psychiatry·Christian Farrell, Johann Brink
Sep 15, 2021·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Naotaka Shinfuku
Nov 5, 2021·Psychiatry Investigation·Yukako NakagamiTakahiro A Kato

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