Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy

Chemical Communications : Chem Comm
Kaimei KeHuang-Hao Yang

Abstract

In this work, we discovered that polypyrrole nanoparticles (PPy NPs) displayed a low non-specific protein adsorption. We herein present the first PPy NP-based biosensing platform for intracellular mRNA detection in living cells. We also demonstrate that PPy NPs exhibit high NIR absorbance and can be utilized for cancer photothermal therapy.

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Citations

Mar 28, 2017·Chemical Society Reviews·Yuqiong XiaXiaoyuan Chen
Aug 24, 2017·Chemical Communications : Chem Comm·Xiaolong ZhangJingfeng Liu
May 15, 2018·Chemistry : a European Journal·Xiao-Qi XuYapei Wang
Sep 22, 2017·Current Medicinal Chemistry·Houjuan ZhuKanyi Pu
Jul 5, 2019·Advanced Materials·Devleena SamantaChad A Mirkin
Dec 21, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Dinggeng HeHung-Wing Li
Nov 26, 2020·ACS Applied Materials & Interfaces·Chengyi HongWeihong Tan

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