PMID: 11905436Mar 22, 2002Paper

Polysaccharide storage myopathy in the M. longissimus lumborum of showjumpers and dressage horses with back pain

Equine Veterinary Journal
E Quiroz-RotheJ L L Rivero

Abstract

This study was designed to investigate whether horses with clinical signs of back pain due to suspected soft tissue injuries were affected by polysaccharide storage myopathy (PSSM). Diagnosis of PSSM in muscle biopsies obtained from the M. longissimus lumborum of 5 showjumpers and 4 dressage horses with a history of back pain is reported. M. longissimus lumborum biopsies of these horses were characterised histopathologically and in 3/9 cases also by electron microscopy. Observations were compared with M. gluteus biopsies of the same horses, and with M. gluteus biopsies obtained from 6 Standardbreds with recurrent exertional rhabdomyolysis and from 6 healthy trotters. M. longissimus biopsies from horses with back pain showed pathognomonic signs of PSSM, i.e. high glycogen and/or abnormal complex amylase-resistant polysaccharide deposits. Similar features were found in M. gluteus biopsies of the same horses. Sections of horses with rhabdomyolysis had increased PAS stain when compared with healthy horses, but did not show amylase-resistant material. Qualitative observations were corroborated by quantitative histochemistry (optical densities) of sections stained with PAS and amylase PAS. This study demonstrated the presence of PSSM...Continue Reading

References

Jan 1, 1992·Neuromuscular Disorders : NMD·S J ValbergS DiMauro
Oct 1, 1980·Equine Veterinary Journal·L B Jeffcott
May 1, 1997·Equine Veterinary Journal·B A ValentineB J Cooper

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Citations

Dec 20, 2007·Equine Veterinary Journal·L M HuntM E McCue
May 28, 2011·Equine Veterinary Journal. Supplement·N C StubbsC M McGowan
May 26, 2017·Equine Veterinary Journal·S J ValbergC J Finno
Apr 4, 2007·Equine Veterinary Journal. Supplement·E MucherE Barrey
Jun 4, 2008·American Journal of Veterinary Research·Anna M FirshmanSalvatore DiMauro
Apr 4, 2007·Equine Veterinary Journal. Supplement·M E McCueS J Valberg
Nov 23, 2005·Veterinary Pathology·B A Valentine, B J Cooper
May 5, 2006·Veterinary Pathology·B A ValentineK A Fischer
Dec 29, 2005·Journal of the American Veterinary Medical Association·Anna M FirshmanStephanie J Valberg
Jun 26, 2015·The Veterinary Record·V E ChamizoJ-L L Rivero
Apr 7, 2021·The Veterinary Clinics of North America. Equine Practice·Kristine L Urschel, Erica C McKenzie
May 13, 2008·The Veterinary Journal·Carrie J FinnoStephanie J Valberg
Mar 24, 2009·The Veterinary Clinics of North America. Equine Practice·Erica C McKenzie, Anna M Firshman

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