Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities

International Journal of Biological Macromolecules
Weihua JinQuanbin Zhang

Abstract

Monthly variations of polysaccharides from Sargassum thunbergii and their anti-complement and anti-tumour activities were investigated. It was observed that an increase in fucose and total sugar contents occurred during the growth period (from early April to mid-June), accompanied by a decrease in molar ratios of other monosaccharides to fucose. The highest yields were obtained from early July to early September, which was in accordance with the significant increase in molar ratio of glucose to fucose and decrease in molar ratio of other monosaccharides to fucose. And the above results suggested that S. Thunbergii synthesized large amount of laminaran, the storage substance of brown algae, during the senescence period. However, sulfate contents were relatively stable in the life cycle of S. thunbergii. These results suggested that S. thunbergii synthesized complex sulfated heteropolysacchairdes during inactive period, while during other periods, it synthesized more sulfated galactofucan. All polysaccharides showed anti-complement activity, suggesting that the harvesting time did not influence the anti-complement activities. In the anti-tumour assay in vitro, the polysaccharides taken during the senescence period had much lower ...Continue Reading

Citations

Aug 30, 2019·Current Pharmaceutical Design·Soraya SajadimajdRoja Rahimi
Jul 13, 2020·International Journal of Biological Macromolecules·Weihua JinWeihong Zhong
Jul 15, 2020·International Journal of Biological Macromolecules·Roza V UsoltsevaSvetlana P Ermakova
Aug 9, 2021·Carbohydrate Polymers·Yuan Yao, Evelyn K F Yim

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