Polysensitization in recurrent lip dermatitis

Journal of Cutaneous Medicine and Surgery
Kathleen Fraser, Melanie D Pratt

Abstract

In allergic contact dermatitis (ACD), polysensitization consists of positive patch test reactions to three or more unrelated allergens. The purpose of this case report is to document a 27-year-old female with recurrent lip dermatitis, polysensitization, and reactions to a number of clinically relevant exposures. Patch testing results revealed positive reactions to tixocortol-21-pivalate (3+), lanolin (3+), neomycin (3+), nickel (1+), hydroxyethyl methylacrylate (3+), bacitracin (3+), and abitol (3+). The patient had seven positive reactions, meeting the criteria for polysensitization. Of known clinical relevance, the patient had applied lanolin-containing lip balms and hydrocortisone- and bacitracin-containing products to the lips, all of which she was strongly reactive to on patch testing. Polysensitization occurs when three or more unrelated allergens are positive on patch testing. This case highlights the importance of considering polysensitization in ACD as numerous allergens that were positive on patch testing were clinically relevant.

References

Apr 16, 2003·Contact Dermatitis·Götz A WestphalKristian Reich
Dec 6, 2003·The Journal of Allergy and Clinical Immunology·Kristian ReichAxel Schnuch
Jan 27, 2006·Allergy·J BraschUNKNOWN German Contact Dermatitis Research Group (DKG) and the Information Network of Departments of Dermatology (IVDK)
Jul 14, 2007·Contact Dermatitis·Berit Christina CarlsenJeanne Duus Johansen
Dec 1, 2007·The Journal of Investigative Dermatology·Natalija NovakStephan Weidinger
Aug 8, 2009·Contact Dermatitis·Berit Christina CarlsenJeanne Duus Johansen
Mar 23, 2012·Contact Dermatitis·Mariette J C NagtegaalThomas Rustemeyer
Mar 12, 2013·Dermatitis : Contact, Atopic, Occupational, Drug·Erin M WarshawHoward I Maibach
Apr 16, 2013·Journal of the American Academy of Dermatology·Dana Malajian, Donald V Belsito
May 8, 2013·The British Journal of Dermatology·J SchwitullaW Uter

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