PMID: 8597583Feb 16, 1996Paper

Polyunsaturated fatty acid composition of the salmon (Salmo salar L.) pineal organ: modification by diet and effect on prostaglandin production

Biochimica Et Biophysica Acta
R James HendersonM T Park

Abstract

To examine the influence of dietary polyunsaturated fatty acids (PUFA) on the lipid composition of the pineal organ and its production of prostaglandins, Atlantic salmon were fed diets containing either fish oils rich in long-chain n-3 polyunsaturated fatty acids, or plant oils with high levels of 18:2(n-6) (sunflower oil) or 18:3(n-3) (linseed oil) for 12 weeks. Lipid content and lipid class composition of the pineal organ were not greatly influenced by the type of oil fed to the fish: choline phosphoglycerides were always the predominant lipid class and the proportion of polar lipids exceeded that of neutral lipids. The pattern of PUFA present in total lipid and individual lipid classes was, however, related to that of the dietary oil. The major PUFA in pineal total lipid from all four dietary groups was 22:6(n-3) and the proportion of n-6 PUFA present was highest in lipid from salmon fed sunflower oil. Both PGE and PGF analogues of the 2- and 3-series were detected in pineal homogenates from all dietary groups with the former prostaglandin being the most abundant. The ratio of PGE2/PGE3 was greatest in fish fed sunflower oil and lowest in those fed linseed oil. The results provide further evidence that despite its anatomical...Continue Reading

References

Dec 15, 1978·Science·S A BinkleyK B Reilly
May 1, 1969·Journal of Neurochemistry·J BasinskaH C Stancer

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Citations

Oct 16, 2015·Molecular Immunology·Victoria Gómez-Abellán, María P Sepulcre
Sep 18, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Jean-Christophe DelpechSophie Layé
Jun 14, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Wen LiuRichard J Kulmacz
Feb 12, 2000·Prostaglandins, Leukotrienes, and Essential Fatty Acids·D R Abayasekara, D C Wathes
Nov 1, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·R GangaM S Izquierdo

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