Abstract
Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to environmental neurotoxicants. The aim of this work was to assess whether maternal dietary intake of PUFAs during pregnancy is positively associated with child neurodevelopment, whose mothers were environmentally exposed to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT). A prospective cohort study with 276 mother-child pairs was performed in Mexico. Neurodevelopment was assessed by Bayley Scales II from children age 1 to 30 months. Dietary PUFAs intake was estimated by Food Frequency Questionnaire at 1st and 3rd trimester of pregnancy. DDE (1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene, the main metabolite of DDT) maternal serum levels were determined by electron capture gas chromatography. Longitudinal multivariate linear mixed-effects analysis, which combines mental (MDI) and motor (PDI) Bayley scales in a single model, were performed. Our results show that in a sample environmentally exposed to DDT, maternal ingestion of DPA during the first trimester of pregnancy was positively associated with MDI (β = 0.10, 95% CI ...Continue Reading
References
Apr 1, 1997·The American Journal of Clinical Nutrition·W C WillettL H Kushi
Jun 9, 1998·Salud pública de México·M Hernández-AvilaW Willett
Jun 15, 2000·Environmental Health Perspectives·D Rice, S Barone
Jul 3, 2002·Pediatrics·Ahmed GomaaMauricio Hernandez-Avila
Jan 2, 2003·Pediatrics·Ingrid B HellandChristian A Drevon
Sep 16, 2003·International Journal of Hygiene and Environmental Health·Keith E ChanonVictor H Borja-Aburto
Aug 18, 2004·Journal of the American College of Nutrition·Paola BenattiMenotti Calvani
Jul 29, 2005·Critical Reviews in Food Science and Nutrition·M Fleith, M T Clandinin
Oct 6, 2005·Environmental Health Perspectives·Kim N DietrichRobert F Berman
Apr 14, 2007·Environmental Health Perspectives·Luisa Torres-SánchezLizbeth López-Carrillo
Oct 13, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mary S WolffNat Rothman
Jul 2, 2008·Neurotoxicology·J J StrainThomas W Clarkson
Sep 8, 2009·Neurotoxicology·Luisa Torres-SánchezLizbeth López-Carrillo
Jul 27, 2010·Progress in Lipid Research·Gunveen KaurAndrew J Sinclair
Apr 5, 2011·Nutrition Reviews·Suzanne J MeldrumKaren Simmer
May 25, 2012·The British Journal of Nutrition·Cristina CampoyRicardo Uauy
Jul 31, 2012·Neuropharmacology·Dirk W Luchtman, Cai Song
Sep 28, 2012·The Journal of Nutrition·J J StrainGary J Myers
Feb 1, 2013·The American Journal of Clinical Nutrition·Jacqueline F GouldMaria Makrides
Jun 12, 2013·Current Medicinal Chemistry·R CrupiS Cuzzocrea
Aug 2, 2013·The Journal of Nutrition·Jonathan Y BernardUNKNOWN EDEN Mother-Child Cohort Study Group
Feb 5, 2014·Journal of Consulting and Clinical Psychology·Scott A BaldwinDavid C Atkins
Jul 1, 2014·Child and Adolescent Psychiatric Clinics of North America·Rachel V Gow, Joseph R Hibbeln
Mar 12, 2015·Pediatric Research·Jonathan Y BernardUNKNOWN EDEN Mother-Child Cohort Study Group
Nov 15, 2016·Annals of Nutrition & Metabolism·Suzanne Meldrum, Karen Simmer
Apr 20, 2017·Nutrition Journal·Hyejin KimNamsoo Chang
Oct 24, 2017·Lancet·Philip J LandriganMa Zhong
Apr 6, 2018·Environmental Pollution·Rafael Ogaz-GonzálezLizbeth López-Carrillo
Feb 1, 2004·Child and Adolescent Mental Health·Vasiliki Totsika, Kathy Sylva