Polyunsaturated fatty acids and conjugated linoleic acid isomers in breast milk are associated with plasma non-esterified and erythrocyte membrane fatty acid composition in lactating women

The British Journal of Nutrition
Alexandre G TorresNádia M F Trugo

Abstract

Maternal adipose tissue is a major contributor to breast milk long-chain fatty acids, probably through the pool of plasma NEFA. The fatty acid composition of the erythrocyte membrane (EM) is a biochemical index of the intake of fatty acids not synthesized endogenously and of PUFA and long-chain PUFA fatty acid status. The present study investigated the associations between breast milk fatty acid composition and the composition of plasma NEFA and of EM fatty acids with special reference to PUFA, long-chain PUFA and conjugated linoleic acid (CLA). The detailed fatty acid composition of mature breast milk was also reported. Thirty-three healthy, lactating Brazilian women donated milk samples; of these, twenty-four also donated blood samples in an observational cross-sectional study. Breast milk fatty acid composition presented several associations with NEFA and EM composition, which explained most (> or =50 %) of the variability of selected milk PUFA, long-chain PUFA and CLA. Milk CLA was associated with fatty acids that are markers of dairy fat intake in the diet, NEFA and EM. In general, breast milk n-3 fatty acids and CLA, but not n-6 fatty acids, were associated with EM composition, whereas both the n-6 and n-3 fatty acids and...Continue Reading

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Citations

Jul 4, 2012·European Journal of Nutrition·Angeliki AntonakouAntonia-Leda Matalas
May 15, 2013·Jornal de pediatria·Renata Y NishimuraDaniela S Sartorelli
Oct 16, 2012·Clinica Chimica Acta; International Journal of Clinical Chemistry·Fan ShenSongmei Liu
Nov 11, 2016·Lipids·Roseli de Souza Santos da CostaMaria das Graças Tavares do Carmo
Mar 17, 2009·Revista de saúde pública·Alexandre G Torres, Nádia M F Trugo
Jun 2, 2017·Journal of Agricultural and Food Chemistry·Matthew J KuhnLorraine M Sordillo
Jun 29, 2011·International Journal of Food Sciences and Nutrition·Pérola RibeiroPatrícia de Oliveira Carvalho
Apr 8, 2020·International Journal of Food Sciences and Nutrition·Maryam BahreynianRoya Kelishadi
May 13, 2018·Reproduction : the Official Journal of the Society for the Study of Fertility·Lindsay EllsworthBrigid Gregg
Jul 25, 2019·Nutrients·Agnieszka Bzikowska-JuraDorota Szostak-Węgierek
Feb 10, 2009·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Flavia MenesesNadia M F Trugo

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