Polyurethane-coated, self-expandable biliary stent: an experimental study

Academic Radiology
A SeveriniA Motta

Abstract

We describe a self-expanding metallic biliary Gianturco-Rösch stent coated with polymeric material. The coating was designed to prevent the growth of neoplastic and reactive tissue within the biliary ducts. The stents were coated with a solvent-casting technique, which consists of dissolving polyurethane (polyether urethane or polycarbonate urethane) pellets in a solvent (dimethylacetamide), dipping the stent in the solution, and completely evaporating the solvent. In vitro mechanical characterization of the stent was performed to determine the adhesion of the coating to the metallic cage, the best introducer caliber for implantation of the device, and the relationship between the stent's diameter and radial stress. Reports in the literature on the biostability of polycarbonate urethane compared with polyether urethane prompted us to use the former material to coat the stents. The solvent technique gives a smooth internal surface of the stent wall, leaving in relief the coated structure of the stent on the external surface. The functional tests demonstrated that the coating did not compromise the original characteristics of the stent in terms of self-expandability, axial flexibility, and increased radial rigidity of the device....Continue Reading

References

Nov 1, 1992·Cardiovascular and Interventional Radiology·F MaccioniP Rossi
Oct 1, 1988·Journal of Biomaterials Applications·M Szycher

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Citations

Dec 17, 2002·Journal of Biomedical Materials Research. Part a·Yasuhide NakayamaTakehisa Matsuda
Oct 29, 2003·Cardiovascular Radiation Medicine·Yasuhide NakayamaHatsue Ishibashi-Ueda
Nov 11, 1999·Cardiovascular and Interventional Radiology·A SeveriniR Doci
Nov 25, 2003·Neurosurgery·Shogo NishiTakehisa Matsuda
Jul 19, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Hans GollwitzerAxel Stemberger
Jul 15, 2005·The International Journal of Artificial Organs·Y NakayamaY Nemoto

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