Pontine atypical neurocytoma: case report

Neurosurgery
Bradley M SwinsonAnthony T Yachnis

Abstract

Neurocytomas are typically located within the supratentorial ventricular system. Extraventricular neurocytomas are very rare, and this is only the second reported case of a pontine neurocytoma. We discuss the clinical presentation, histology, and treatment of these rare tumors. A 58-year-old man presented with a 4-month history of headache and unilateral facial and distal extremity paresthesia. Magnetic resonance imaging (MRI) scans demonstrated a 2.6 x 2.2-cm ring-enhancing cystic mass in the right pons. MRI-guided stereotactic biopsy yielded a diagnosis of atypical neurocytoma. Because of the location and malignant histological features of the tumor, the patient was initially treated with external beam radiation therapy. Several months later, MRI scans demonstrated tumor progression. The patient then underwent three rounds of temozolomide chemotherapy, during and after which his symptoms worsened. Aggressive subtotal resection of the tumor was achieved via a right suboccipital craniectomy. Twenty-eight months postoperatively, the patient is symptom free, and MRI scans demonstrate no evidence of residual or recurrent tumor.

References

Jan 1, 1992·Journal of Neurosurgery·M G YasargilO D Wiestler
Dec 1, 1990·Journal of Neuro-oncology·D N LouisE T Hedley-Whyte
Jan 1, 1986·Acta Neuropathologica·J J Townsend, J P Seaman
Jan 1, 1982·Acta Neuropathologica·J HassounM Toga
Jan 1, 1994·British Journal of Neurosurgery·S SgourosP Barber
Oct 1, 1994·Surgical Neurology·S SgourosM P Carey
Aug 1, 1994·Journal of Neurosurgery·S B TatterD N Louis
Jan 1, 1994·Acta Neuropathologica·S CocaJ Vaquero
Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer
Jul 1, 1993·Brain Pathology·J HassounP Kleihues
Jun 1, 1993·The British Journal of Ophthalmology·C MetcalfI McAllister
Feb 15, 1997·Cancer·S E SchildM K Lyons
Sep 1, 1996·Journal of Clinical Pathology·V Soontornniyomkij, R I Schelper
Feb 1, 1997·The American Journal of Surgical Pathology·F GiangasperoP C Burger
Mar 1, 1997·Journal of Neurosurgery·D Y EngK Jaeckle
Apr 1, 1997·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·L HirschowitzS Love
May 1, 1997·Journal of Neuropathology and Experimental Neurology·F SöylemezogluP Kleihues
Jul 1, 1997·Journal of Neurosurgery·S A EnamK L Ho
Jul 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·S R StapletonB N Harding
Jul 1, 1997·Acta Neuropathologica·H FunatoM Aoyagi
Sep 1, 1997·Journal of Neuro-oncology·D DoddsR Rampling
Feb 11, 1998·Surgical Neurology·S SgourosA Jackowski
Apr 13, 1999·Journal of Neurosurgery·C L StephanF Chamberlin
Jun 19, 2001·American Journal of Clinical Oncology·D M BrownH G Brown
Nov 2, 2001·The American Journal of Surgical Pathology·D J BratP C Burger
Nov 13, 2001·Journal of Neurosurgery·E Tyler-KabaraL D Lunsford
Mar 16, 2002·Journal of Neuropathology and Experimental Neurology·Paul KleihuesWebster K Cavenee
Aug 16, 2002·Acta neurochirurgica·A J MartinS F D Robinson
Sep 25, 2002·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ji Hoon ShinDae Chul Suh
Oct 23, 2002·Neurology·Dirk Rades, Fabian Fehlauer
Nov 21, 2002·Pathology, Research and Practice·Anna Maria BuccolieroGian Luigi Taddei
Jul 5, 2003·Virchows Archiv : an International Journal of Pathology·Nicolaus FriedrichsReinhard Buettner
Feb 11, 2004·Cancer·Dirk RadesSteven E Schild
Mar 16, 2004·Journal of Neuro-oncology·Meic H SchmidtMichael W McDermott

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Citations

Jan 16, 2008·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Guzide A GokhanRecai Tuncer
Mar 3, 2012·The Oncologist·German Reyes-BoteroFlorence Laigle-Donadey
Nov 8, 2011·Journal of Neurosurgery·Ari J KaneAndrew T Parsa
Jul 2, 2008·Journal of Neurosurgery. Pediatrics·Ali I RajaIan F Pollack
Dec 21, 2013·Acta neurochirurgica·Akshay S PatilS Nair
Aug 21, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Marta NavasJose A Jimenez
Nov 30, 2014·Neurosurgery Clinics of North America·Fadi B SweissJonathan H Sherman
Apr 2, 2008·Journal of Computer Assisted Tomography·Shiori AmemiyaKuni Ohtomo
Jan 29, 2013·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Anatoly Shuster, Mehran Midia
Apr 20, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Shaun ChouThomas Ng
Mar 18, 2011·Cytopathology : Official Journal of the British Society for Clinical Cytology·N GhosalA S Hegde
Jun 1, 2016·Case Reports in Neurological Medicine·Angela SpurgeonN Scott Litofsky
Nov 12, 2014·Journal of Neuro-oncology·Zhongwei XiongJincao Chen
Jul 7, 2011·Journal of Neuro-oncology·Ali GencTurker Kilic
Mar 16, 2018·Molecular and Clinical Oncology·Zhimin LiYongning Li
Aug 1, 2018·Journal of Neuro-oncology·Muliang JiangChiShing Zee
Apr 27, 2020·La Radiologia medica·Nicola RomanoAntonio Castaldi
Mar 23, 2018·Molecular and Clinical Oncology·Yi-Hung KuoChih-Chien Chin

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