Pontomedullary rent. A specific type of primary brainstem traumatic injury

The American Journal of Forensic Medicine and Pathology
W EzzatJ Nyssen

Abstract

Pontomedullary rent is a primary injury to the brainstem that may occur in high-speed accidents. We present a series of 13 autopsies with complete or partial pontomedullary rent documented over a 12-year period. Of the 13 cases, seven had associated basal skull fractures and three had fractures of the cervical spine. In five patients, the rent was an isolated traumatic lesion of the brain. While pontomedullary rents are mostly caused by traumatic craniocervical hyperextension, some authors feel that these rents could be a form of diffuse axonal injury caused by angular acceleration of the head. In this study, two patients had documented features of diffuse axonal injury. More than one mechanism of injury could therefore be involved. Pontomedullary rents could be underdiagnosed, as partial rent is compatible with survival and, when there are no associated fractures, these tears may be attributed to artifactual damage occurring during removal of the brain at autopsy.

Citations

Dec 27, 2011·Forensic Science, Medicine, and Pathology·Vladimir ŽivkovićMarija Djurić
Nov 26, 2005·Neurologia Medico-chirurgica·Kouichi HiraiwaNamio Kodama
Dec 24, 2019·Forensic Science International : Synergy·Lucile TuchtanLionel Thollon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.