Poor-Grade Aneurysmal Subarachnoid Hemorrhage: Factors Influencing Functional Outcome--A Single-Center Series

World Neurosurgery
Patrick SchussErdem Güresir

Abstract

Patients presenting with poor-grade aneurysmal subarachnoid hemorrhage (SAH) have commonly been reported to have a poor prognosis; however, several reports suggest a favorable outcome in a subgroup of patients. We analyzed our database to identify factors determining functional outcome after poor-grade SAH. During the period 2004-2014, 248 patients with poor-grade SAH were treated in our institution. Poor-grade SAH was defined as World Federation of Neurological Surgeons grades IV-V on admission. Data including patient characteristics, treatment modality, radiologic features, and functional neurologic outcome were assessed and further analyzed. Outcome was assessed according to the modified Rankin Scale after 6 months and stratified into favorable (modified Rankin Scale score 0-2) versus unfavorable (modified Rankin Scale score 3-6). A multivariate analysis was performed to identify predictors of functional outcome. A favorable outcome was achieved in 24% of patients with poor-grade SAH. Patients with a favorable outcome were significantly younger (P = 0.005), harbored significantly smaller aneurysms (P = 0.004), and had a lower initial World Federation of Neurological Surgeons grade (P < 0.0001). An unfavorable outcome was sig...Continue Reading

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Citations

Nov 2, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Y Z Al-Tamimi
Feb 12, 2017·Journal of Neurointerventional Surgery·Kyle M FargenJoshua A Hirsch
Feb 2, 2019·Current Neurovascular Research·Jianfeng ZhengXiaochuan Sun
Sep 22, 2016·Neurocritical Care·Airton Leonardo de Oliveira ManoelR Loch Macdonald
Jul 17, 2020·Neurocritical Care·Mónica Mourelo-FariñaRita Galeiras
Jul 14, 2020·Anaesthesia and Intensive Care·Minny OjhaMatthew J Maiden
Dec 29, 2020·Neurosurgery·James FeghaliRafael J Tamargo
May 15, 2021·BMC Neurology·Elisa Gouvêa BogossianFabio Silvio Taccone
Jun 14, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Lukas GoertzBoris Krischek

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