Poor sensitivity of routine fetal anomaly ultrasound screening for antenatal detection of atrioventricular septal defect

Heart
H ter HeideJ L Gibbs

Abstract

To report the antenatal detection rate in a consecutive series of liveborn infants with atrioventricular septal defect (AVSD). Review and analysis of referrals for detailed fetal echocardiography and postnatal diagnosis of AVSD. Tertiary referral centre for congenital heart disease centre with data prospectively collected between 1996 to 2001. 92 consecutively liveborn infants with AVSDs were identified of which 27 (29%) were detected by routine obstetric antenatal ultrasound. The antenatal diagnosis rate was worse for liveborn infants with trisomy 21 (12 of 49 (25%) v 15 of 43 (35%) chromosomally normal children) and for infants with AVSD without other structural heart disease (18 of 74 (24%) v 9 of 18 (50%) infants with associated structural heart disease). Despite the potential ability of fetal ultrasound to detect AVSDs, the antenatal diagnosis rate is poor. This is particularly true for infants with trisomy 21 and is of importance when counselling parents with an apparently normal fetal ultrasound scan.

References

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Citations

Feb 15, 2005·Prenatal Diagnosis
May 6, 2014·Journal of Pregnancy·Mariza Rumi KataguiriAntonio Fernandes Moron
Jun 21, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Makarios EleftheriadesDemetrios Botsis
Aug 26, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniC Nappi
Jun 24, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L Allan
Oct 18, 2015·International Journal of Cardiology·Emmeline E CalkoenMonique R M Jongbloed
Jun 9, 2017·Seminars in Cardiothoracic and Vascular Anesthesia·Faith J RossGregory J Latham

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