PMID: 11339919May 8, 2001Paper

Population-based study of microinvasive adenocarcinoma of the uterine cervix

Obstetrics and Gynecology
Joel C WebbHarriet O Smith

Abstract

To analyze lymph node status and survival rates of women with microinvasive cervical adenocarcinoma (International Federation of Gynecology and Obstetrics stages IA(1) and IA(2)). The Surveillance, Epidemiology, and End Results (SEER) Public-Use Database was used to identify cases of microinvasive cervical adenocarcinoma diagnosed between 1988 and 1997. Variables analyzed included stage, extent of surgery, lymph node status, radiation therapy, and age. Statistics included analysis of trends, analysis of variance, log-rank test, one-sided binomial confidence interval estimation, and power analysis. Among 301 reported cases, 131 had stage IA(1) and 170 IA(2) disease. Simple hysterectomies were done in 54 women with IA(1) and 64 with IA(2) disease and radical hysterectomies were done in 50 and 83 women, respectively. Only one of 140 women who had lymphadenectomy had a single positive lymph node. There were four tumor-related deaths (one with IA(1), and three with IA(2) disease). There were no deaths among 96 women (47, IA(1); 49, IA(2)) treated by simple hysterectomy alone. The mean follow-up was 46.5 months (range 1--119). The censored survival rate was 98.7% overall (99.2% IA(1), 98.2% IA(2)). Power analysis estimated that 720 p...Continue Reading

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Citations

Dec 17, 2003·Gynecologic Oncology·Jayanthi S LeaJohn O Schorge
Sep 28, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Richard J Zaino
Feb 15, 2011·Journal of Lower Genital Tract Disease·Sarah M BeanTerence J Colgan
Oct 4, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ericka WiebeGillian Thomas
May 30, 2012·Obstetrics and Gynecology Clinics of North America·Clare Reade, Laurie Elit
Nov 2, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Sukanda MahawerawatCharuwan Tantipalakorn Sae-Teng
May 2, 2006·Obstetrics and Gynecology·David H Moore
Feb 28, 2015·The American Journal of Surgical Pathology·Andres A RomaElvio G Silva
Apr 3, 2014·The Journal of Obstetrics and Gynaecology Research·Jung-Yun LeeYong-Sang Song
Aug 21, 2002·Medical Care·Beth A VirnigJean Freeman

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