PMID: 8266404Sep 1, 1993

Population-based study of serum hepatitis B virus DNA in Gabon

Transactions of the Royal Society of Tropical Medicine and Hygiene
M C DazzaB Larouzé

Abstract

The prevalence of serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) was measured in a Gabonese community at high risk for HBV infection. Among 698 subjects 5 to 24 years old, the prevalence of HBsAg was 11.1% vs. 57.9% for anti-HBs and 7.2% for anti-HBc alone. The prevalence of HBeAg among HBsAg-positive subjects was 26.5% vs. 59.5% for anti-HBe. The prevalence of HBV DNA tested by a hybridization spot test was 2.1% in the overall population and 18.7% among HBsAg-positive subjects. HBV DNA was found in 15 of 21 HBeAg-positive subjects but in none of the subjects positive for anti-HBe or negative for both HBeAg and anti-HBe. HBV DNA was not detected in any HBsAg negative subjects. The prevalence of HBV DNA decreased with age. This low prevalence of HBV DNA contrasts with the high level of endemicity in the study population.

References

Jun 1, 1990·The Journal of Infectious Diseases·H WhittleA J Hall
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J R WandsC Bréchot
May 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S D LeeM J Tong
May 1, 1985·The Journal of Pediatrics·E MarinierB S Blumberg
May 1, 1983·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J ScottoC Bréchot
Sep 1, 1981·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F BoninoJ Gerin
Feb 1, 1981·American Journal of Epidemiology·W SzmunessE J Harley

Citations

Mar 1, 1996·Journal of Medical Virology·F E MartinsonS M Lemon
Nov 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·E DelaporteB Larouzé
Jan 21, 2011·PloS One·O Ouwe-Missi-Oukem-BoyerS Bisser
Mar 25, 2016·Diagnostic Microbiology and Infectious Disease·Eva MortensenMark Holodniy
Jan 5, 1999·International Journal of STD & AIDS·C E Sterk
Jul 19, 2006·Journal of Medical Virology·M MakuwaFrançois Simon

Related Concepts

DNA, Viral
Hepatitis B
Hepatitis B Antibodies
Hepatitis B Core Antigen
HBe Ag-2
Hepatitis B Surface Antigens
Dane Particle

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