Population coding in area V4 during rapid shape detections

Journal of Neurophysiology
Katherine F Weiner, Geoffrey M Ghose

Abstract

While previous studies have suggested that neuronal correlations are common in visual cortex over a range of timescales, the effect of correlations on rapid visually based decisions has received little attention. We trained Macaca mulatta to saccade to a peripherally presented shape embedded in dynamic noise as soon as the shape appeared. While the monkeys performed the task, we recorded from neuronal populations (5-29 cells) using a microelectrode array implanted in area V4, a visual area thought to be involved in form perception. While modest correlations were present between cells during visual stimulation, their magnitude did not change significantly subsequent to the appearance of a shape. We quantified the reliability and temporal precision with which neuronal populations signaled the appearance of the shape and predicted the animals' choices using mutual information analyses. To study the impact of correlations, we shuffled the activity from each cell across observations while retaining stimulus-dependent modulations in firing rate. We found that removing correlations by shuffling across trials minimally affected the reliability or timing with which pairs, or larger groups of cells, signaled the presence of a shape. To a...Continue Reading

References

Oct 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·A K EngelW Singer
Nov 1, 1974·Psychological Review·P M Milner
Dec 9, 1998·Nature·V A Lamme, H Spekreijse
Feb 9, 1999·Neural Computation·L F Abbott, P Dayan
Jun 8, 2001·Nature·S NirenbergP E Latham
Nov 8, 2001·Journal of Neurophysiology·A Pasupathy, C E Connor
Apr 4, 2002·Journal of Neurophysiology·Geoffrey M GhoseJohn H R Maunsell
Apr 27, 2002·Nature Neuroscience·M E Mazurek, M N Shadlen
Jan 3, 2003·Nature Cell Biology·Paul ChangTim Stearns
Jul 2, 2004·Neural Computation·R Quian QuirogaY Ben-Shaul
Aug 24, 2004·Nature Neuroscience·Pieter R RoelfsemaHenk Spekreijse
Apr 9, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adam Kohn, Matthew A Smith
Apr 26, 2005·Neuron·Ben J A Palanca, Gregory C DeAngelis
May 27, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Peter E Latham, Sheila Nirenberg
Nov 4, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Toshiyuki Hirabayashi, Yasushi Miyashita
Dec 27, 2005·Vision Research·Wolfgang EinhäuserPeter König
Mar 24, 2006·Journal of Neurophysiology·Bruno B Averbeck, Daeyeol Lee
Aug 8, 2006·Journal of Vision·Geoffrey M Ghose
May 27, 2008·Vision Research·Tirin Moore, Mindy H Chang
Jun 20, 2008·Journal of Neurophysiology·Pedro MaldonadoSonja Grün
Nov 28, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew A Smith, Adam Kohn
Dec 26, 2008·Journal of Neurophysiology·Geoffrey M Ghose, Ian T Harrison
Jan 17, 2009·Journal of Vision·Yi DongErnst Niebur
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Brad C Motter
Aug 12, 2009·Frontiers in Integrative Neuroscience·Peter J UhlhaasWolf Singer
Nov 17, 2009·Nature Neuroscience·Marlene R Cohen, John H R Maunsell
Jan 11, 2011·Nature Neuroscience·Arnulf B A GrafJ Anthony Movshon
May 18, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yanxia PanWei Wang
Jun 15, 2012·Journal of Neurophysiology·Nicolas Y MasseErik P Cook
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philipp BerensAndreas S Tolias
Mar 22, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew A Smith, Marc A Sommer
May 10, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ian T HarrisonGeoffrey M Ghose
Sep 10, 2014·Nature Neuroscience·Rubén Moreno-BoteAlexandre Pouget
Oct 4, 2014·Frontiers in Neuroscience·Katherine F Weiner, Geoffrey M Ghose

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Citations

Aug 2, 2018·Journal of Neurophysiology·Bryan M Krause, Geoffrey M Ghose

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