Population coding of reward magnitude in the orbitofrontal cortex of the rat.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Esther van DuurenCyriel M A Pennartz

Abstract

Although single-cell coding of reward-related information in the orbitofrontal cortex (OFC) has been characterized to some extent, much less is known about the coding properties of orbitofrontal ensembles. We examined population coding of reward magnitude by performing ensemble recordings in rat OFC while animals learned an olfactory discrimination task in which various reinforcers were associated with predictive odor stimuli. Ensemble activity was found to represent information about reward magnitude during several trial phases, namely when animals moved to the reward site, anticipated reward during an immobile period, and received it. During the anticipation phase, Bayesian and template-matching reconstruction algorithms decoded reward size correctly from the population activity significantly above chance level (highest value of 43 and 48%, respectively; chance level, 33.3%), whereas decoding performance for the reward delivery phase was 76 and 79%, respectively. In the anticipation phase, the decoding score was only weakly dependent on the size of the neuronal group participating in reconstruction, consistent with a redundant, distributed representation of reward information. In contrast, decoding was specific for temporal s...Continue Reading

Citations

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Jan 15, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Shunsuke KobayashiWolfram Schultz
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