Dec 8, 2004

Population genetic structure of Anopheles gambiae mosquitoes on Lake Victoria islands, west Kenya

Malaria Journal
Hong ChenGuiyun Yan

Abstract

Understanding the genetic structure of island Anopheles gambiae populations is important for the current tactics in mosquito control and for the proposed strategy using genetically-modified mosquitoes (GMM). Genetically-isolated mosquito populations on islands are a potential site for testing GMM. The objective of this study was to determine the genetic structure of A. gambiae populations on the islands in Lake Victoria, western Kenya. The genetic diversity and the population genetic structures of 13 A. gambiae populations from five islands on Lake Victoria and six villages from the surrounding mainland area in the Suba District were examined using six microsatellite markers. The distance range of sampling sites varied between 2.5 and 35.1 km. A similar level of genetic diversity between island mosquito populations and adjacent mainland populations was found. The average number of alleles per locus was 7.3 for the island populations and 6.8 for the mainland populations. The average observed heterozygosity was 0.32 and 0.28 for the island and mainland populations, respectively. A low but statistically significant genetic structure was detected among the island populations (FST = 0.019) and between the island and mainland populat...Continue Reading

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References

Mentioned in this Paper

Genetic Drift
Computer Software
Neuro-Oncological Ventral Antigen 2
Study
Short Tandem Repeat
Morbidity Aspects
Dysequilibrium Syndrome
Genetics, Population
Polymerase Chain Reaction Analysis
Pyrethrum (plant)

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