Population structure of the fish-pathogenic bacterium Flavobacterium psychrophilum.

Applied and Environmental Microbiology
Pierre NicolasEric Duchaud

Abstract

Flavobacterium psychrophilum is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide, and its control mainly relies on antibiotic treatments. To better understand the population structure of this bacterium and its mode of evolution, we have examined the nucleotide polymorphisms at 11 protein-coding loci of the core genome in a set of 50 isolates. These isolates were selected to represent the broadest possible diversity, originating from 10 different host fish species and four continents. The nucleotide diversity between pairs of sequences amounted to fewer than four differences per kilobase on average, corresponding to a particularly low level of diversity, possibly indicative of a small effective-population size. The recombination rate, however, seemed remarkably high, and as a consequence, most of the isolates harbored unique combinations of alleles (33 distinct sequence types were resolved). The analysis also showed the existence of several clonal complexes with worldwide geographic distribution but marked association with particular fish species. Such an association could reflect preferential routes of transmission and/or adaptive niche specialization. The analysis provided ...Continue Reading

References

Feb 1, 1974·Genetical Research·J M Smith, J Haigh
Apr 18, 1998·Proceedings of the National Academy of Sciences of the United States of America·M C MaidenB G Spratt
May 15, 1998·Molecular Biology and Evolution·J Maynard Smith, N H Smith
Dec 5, 1998·Diseases of Aquatic Organisms·C ChakrounJ F Bernardet
Jul 28, 1999·Research in Microbiology·C MichelR P Hedrick
Jan 3, 2001·Proceedings of the National Academy of Sciences of the United States of America·E J FeilB G Spratt
Jan 25, 2003·Diseases of Aquatic Organisms·Jari MadetojaTom Wiklund
Oct 15, 2003·Trends in Microbiology·Rachel Urwin, Martin C J Maiden
Dec 5, 2003·Journal of Fish Diseases·A NematollahiF Haesebrouck
Dec 12, 2003·Diseases of Aquatic Organisms·Shotaro IzumiHisatsugu Wakabayashi
Jan 9, 2004·Applied and Environmental Microbiology·B AlvarezJ A Guijarro
Jul 3, 2004·BMC Bioinformatics·Keith A JolleyMartin C J Maiden
Jun 16, 2005·Journal of Clinical Microbiology·Mamuka KotetishviliO Colin Stine
Mar 1, 2006·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Marcos Pérez-LosadaKeith A Crandall
Jun 27, 2007·Nature Biotechnology·Eric DuchaudAbdenour Benmansour
Aug 25, 2007·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Naiel BisharatRosalind M Harding

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Citations

Sep 20, 2011·Applied and Environmental Microbiology·Marie TouchonEric Duchaud
Sep 4, 2013·Diseases of Aquatic Organisms·Nicole StrepparavaOrlando Petrini
Oct 6, 2014·Nature Genetics·Leonor Sánchez-BusóFernando González-Candelas
Mar 19, 2014·Veterinary Microbiology·Ruben Avendaño-HerreraEric Duchaud
Jul 25, 2014·Microbial Biotechnology·Esther GómezJosé A Guijarro
Nov 23, 2017·Frontiers in Microbiology·David Pérez-PascualEric Duchaud
Aug 4, 2018·Journal of Fish Diseases·Maureen JarauJohn S Lumsden
Feb 25, 2014·Applied and Environmental Microbiology·Hanne NilsenTom Wiklund
Oct 3, 2008·The ISME Journal·Michiel Vos, Xavier Didelot
Jan 13, 2019·Applied and Environmental Microbiology·T RochatE Duchaud
Feb 16, 2010·Journal of Animal Science·T D LeedsG D Wiens
Sep 18, 2020·Diseases of Aquatic Organisms·Thorbjorg EinarsdottirSigridur Hjartardottir
Feb 23, 2018·Frontiers in Microbiology·Eric DuchaudPierre Nicolas
Aug 31, 2019·Journal of Fish Diseases·Benjamin R LaFrentzJohn P Shelley
Aug 10, 2019·Frontiers in Microbiology·Krister SundellTom Wiklund

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