PMID: 9545131Apr 17, 1998Paper

Porcine reproductive and respiratory syndrome

Veterinary Pathology
K D Rossow

Abstract

In 1987, porcine reproductive and respiratory syndrome (PRRS) was recognized in the USA as a new disease of swine causing late-term reproductive failure and severe pneumonia in neonatal pigs. The syndrome is caused by an RNA virus referred to as PRRS virus (PRRSV), which is classified in the family Arteriviridae. Swine macrophages are the only indigenous cell type known to support PRRSV replication. Direct contact between infected and naive pigs is the predominant route of PRRSV transmission. Exposure of a mucosal surface to PRRSV leads to virus replication in regional macrophages, a prolonged viremia and systemic distribution of virus to other macrophage populations. Reproductive failure induced by PRRSV infection in late-gestation sows is characterized by premature farrowing of stillborn, partially autolyzed, and mummified fetuses. Pneumonia caused by PRRSV infection is more severe in young pigs compared to adults and may be complicated by concurrent bacterial infections. Gross lung lesions associated with PRRSV infection vary from none to diffuse consolidation. In addition, multiple lymph nodes may be markedly enlarged. Microscopically, PRRSV-pneumonia is characterized by multifocal, interstitial thickening by macrophages an...Continue Reading

References

Apr 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J E CollinsH S Joo
Apr 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D A BenfieldD Chladek
Apr 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·G WensvoortD Chladek
Apr 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·I J YoonG D Dial
Jun 6, 1992·The Veterinary Record·S C Gordon
Jul 1, 1991·The Veterinary Quarterly·G WensvoortF Wagenaar
Jan 1, 1987·Annual Review of Microbiology·D A Steinhauer, J J Holland
Jul 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K J YoonK B Platt
Jul 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·V L CooperN B Harris
Jul 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K J YoonK B Platt
Jul 1, 1995·Journal of Clinical Microbiology·J Christopher-HenningsC C Chase
Jan 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·W L MengelingA C Vorwald
Jan 10, 1995·Virology·J J MeulenbergG Wensvoort
Oct 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K M Lager, M R Ackermann
Jul 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·I J YoonT W Molitor
Jul 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K D RossowJ E Collins
Jan 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K D RossowJ E Collins
Apr 16, 1994·The Veterinary Record·I L VoicuM A Elazhary
Apr 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·P G HalburY Niyo
May 1, 1994·Journal of Virological Methods·P Van WoenselN Visser
Apr 1, 1994·The Journal of Veterinary Medical Science·M ShimizuM Kobayashi
Jun 1, 1993·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·N Stockhofe-ZurwiedenJ Pohlenz
Oct 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D ZemanM Minehart
Oct 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·E M BautistaJ E Collins
Oct 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·W G Van AlstineG W Stevenson
Jul 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·G W StevensonK K Keffaber
Apr 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·E M BautistaJ E Collins

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Citations

May 28, 2019·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Carles VilaltaRobert B Morrison
Mar 24, 2000·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·O IllanesJ Martínez
Feb 3, 1999·Annals of the New York Academy of Sciences·J S Allan
Apr 26, 2000·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·J BeyerH Wege
Apr 27, 2007·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Kenji KawashimaHiroshi Tsunemitsu
Jan 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Caitlin D LemkeJohn E Butler
Jul 19, 2006·Veterinary Pathology·K A MarateaG W Stevenson
Sep 16, 2008·Viral Immunology·Yongming SangFrank Blecha
Feb 26, 2011·Microbiology and Immunology·Hiroshi IsekiHiroshi Tsunemitsu
Dec 24, 2014·American Journal of Veterinary Research·Steven J P TousignantRobert B Morrison
Feb 13, 2015·Journal of Virology·Zhiguang RanWenjun Ma

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