PMID: 7090105Jun 1, 1982Paper

Porcine sensitized lymph node cells (immunotherapy) and attenuated irradiation for infiltrative transitional cells carcinoma of bladder

Urology
A T CockettH M Keys

Abstract

Thirty-four patients wih infiltrative bladder carcinoma, Stage B2C or higher were treated with immunotherapy and irradiation. Seventeen patients are alive, and 17 have succumbed to their disease. Eight patients underwent cystectomy after immunotherapy and irradiation; 6 of 8 are alive and well at the present time. The technique of immunotherapy is outlined. New methodology for sequential CT scans and scheduled bladder biopsies is mentioned. The 17 patients have survived twelve to sixty-nine months after immunotherapy and irradiation. Downstaging is demonstrated based on sequential CT scans of the bony pelvis and histologic biopsy. The biopsies reveal eosinophilia and multinucleated giant cells, a specific response to immunotherapy. A prospective randomized study will be initiated.

Citations

Jan 1, 1985·The Journal of Urology·M J Droller
Jan 18, 2011·Biochemical and Biophysical Research Communications·Dong Xun ZhouHe Ping Hu
Sep 11, 1991·The Journal of Urology·A T CockettL L Wheeless

Related Concepts

Metazoa
Malignant Neoplasm of Urinary Bladder
Carcinoma, Transitional Cell
Immunotherapy
Lymph Nodes
Radiotherapy Dosage
Family suidae
Tomography, X-Ray Computerized Axial

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