Pores with longitudinal irregularities distinguish objects by shape

ACS Nano
Yinghua QiuZuzanna S Siwy

Abstract

The resistive-pulse technique has been used to detect and size objects which pass through a single pore. The amplitude of the ion current change observed when a particle is in the pore is correlated with the particle volume. Up to date, however, the resistive-pulse approach has not been able to distinguish between objects of similar volume but different shapes. In this manuscript, we propose using pores with longitudinal irregularities as a sensitive tool capable of distinguishing spherical and rod-shaped particles with different lengths. The ion current modulations within resulting resistive pulses carry information on the length of passing objects. The performed experiments also indicate the rods rotate while translocating, and displace an effective volume that is larger than their geometrical volume, and which also depends on the pore diameter.

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Citations

Jan 23, 2016·Analytical Chemistry·Hongwen WuQuanjun Liu
Nov 10, 2015·ACS Nano·Martin A EdwardsHenry S White
Oct 7, 2016·Faraday Discussions·Raquel L FraccariTim Albrecht
Dec 9, 2016·Soft Matter·Sébastien BalmeJean-Marc Janot
Dec 16, 2016·Nanoscale·István MakraRóbert E Gyurcsányi
Nov 14, 2017·Electrophoresis·Y M N D Y BandaraJason R Dwyer
Jan 21, 2018·Scientific Reports·Yunlong WangJianguo Tian
Sep 1, 2018·Journal of Nanobiotechnology·Mohamed El IdrissiWolfgang Meier
Jul 16, 2017·Physical Review. E·Dmitriy V MelnikovMaria E Gracheva
Sep 2, 2017·Scientific Reports·Preston HinkleZuzanna S Siwy
Aug 27, 2019·Journal of Electroanalytical Chemistry·Christopher G GundersonBo Zhang
Mar 23, 2018·Entropy·Claire GilpinCraig Martens
Apr 10, 2021·The Journal of Chemical Physics·Wilfred Shelby Russell, Zuzanna Siwy
Nov 9, 2018·Analytical Chemistry·Jingjie ShaYunfei Chen
Oct 14, 2021·Biomedical Microdevices·Mohammad Tajparast, Mladen I Glavinović

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