Poroid hidradenoma in the hand: A case report and systematic review

Journal of Cutaneous Pathology
Robert MillerJames Chan

Abstract

Poroid hidradenoma (PH) is a rare benign neoplasm of the skin appendages. There are currently no guidelines for its management, and little information available regarding the natural history, treatment options, or outcomes. Systematic literature review identified 19 cases of isolated PH. Mean age at presentation was 54 years. Male to female ratio was 3:1, and the majority of cases were in the head and neck region. One-third of lesions were painful or tender. Sizes varied from 0.11 × 0.9 × 0.2 cm (digit) to 6 cm (presternal region). Twelve cases were treated by surgical excision, while the remainder were biopsy specimens. Follow-up was reported in five cases, with a median follow-up of 1 year. No cases of local invasion or spread have been reported, although there was one case of possible recurrence identified 8 years after surgical excision. The presented case is the first to identify a PH on the hand, represents the smallest lesion to date, and was successfully treated by excision. We suggest that PHs be treated by excision and followed up for 6 to 12 months. Given one case of potential (but unconfirmed) recurrence, and no report of malignant transformation, we suggest that narrow margins may be appropriate.

References

Sep 1, 1993·The Journal of Dermatology·S Ichioka, A Yamada
Oct 29, 1998·Journal of the American Podiatric Medical Association·R M WhitmoreT Piper
Mar 30, 2001·International Journal of Dermatology·S ChoJ H Hahm
Nov 28, 2002·The American Journal of Dermatopathology·Salem O AlowamiWedad Hanna
Jun 27, 2006·International Journal of Dermatology·Chih-Chiang ChenHan-Nan Liu
Jun 23, 2007·The Journal of Dermatology·Takashi UenoSeiji Kawana
Feb 1, 2011·Pediatric Dermatology·Verónica LópezEsperanza Jordá

❮ Previous
Next ❯

Citations

Dec 27, 2019·The American Journal of Surgical Pathology·Katharina WiedemeyerThomas Brenn
Jun 4, 2021·Annals of Dermatology·Joon Soo LimSeung Hyun Cheong
Aug 12, 2021·Case Reports in Plastic Surgery & Hand Surgery·M MukitX Jing
Aug 20, 2021·The American Journal of Dermatopathology·Martí Pons BenaventCarlos Monteagudo Castro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Plastic and Reconstructive Surgery
S M MamounD G Richey
Zhonghua bing li xue za zhi Chinese journal of pathology
Yang GuanPeng Li
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen
R WerdinV Schumpelick
Journal of the American Podiatry Association
M J Marcus, J Witkowski
Journal of the American Podiatric Medical Association
S W HayesA J Nardozza
© 2022 Meta ULC. All rights reserved