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Porphyromonas gingivalis cell wall components induce PD-L1 expression on human oral carcinoma cells by a RIP2-dependent mechanism

Infection and Immunity

Feb 12, 2020

S GroegerJ Meyle

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PubMed

Abstract

Programmed death-ligand 1 (PD-L1/B7-H1) serves as a co-signalling molecule in cell-mediated immune responses and contributes to chronicity of inflammation and the escape of tumor cells from immunosurveillance. Here we investigated the molecular mechanisms leading to PD-L1 upregulation o...read more

Mentioned in this Paper

Progressive Disease
Kinase Activity
Protein Expression
Cell Wall
Porphyromonas gingivalis
Porphyromonas
Death Receptor Ligand
Inflammation
RIPK2 protein, human
Mitogen-Activated Protein Kinases
2
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Porphyromonas gingivalis cell wall components induce PD-L1 expression on human oral carcinoma cells by a RIP2-dependent mechanism

Infection and Immunity

Feb 12, 2020

S GroegerJ Meyle

PMID: 32041789

DOI: 10.1128/iai.00051-20

Abstract

Programmed death-ligand 1 (PD-L1/B7-H1) serves as a co-signalling molecule in cell-mediated immune responses and contributes to chronicity of inflammation and the escape of tumor cells from immunosurveillance. Here we investigated the molecular mechanisms leading to PD-L1 upregulation o...read more

Mentioned in this Paper

Progressive Disease
Kinase Activity
Protein Expression
Cell Wall
Porphyromonas gingivalis
Porphyromonas
Death Receptor Ligand
Inflammation
RIPK2 protein, human
Mitogen-Activated Protein Kinases
2

Feeds With Similar Papers

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

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Antoni Ribas, Siwen Hu-Lieskovan
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