PMID: 6974749Sep 1, 1981Paper

Portal vein thrombosis and fatal pulmonary thromboembolism associated with oral contraceptive treatment

Journal of Clinical Gastroenterology
J P CapronJ L Gineston

Abstract

We report a 33-year-old woman who took oral contraceptives for 8 years, and who developed gastrointestinal bleeding from esophageal varices. Celiac and mesenteric angiography demonstrated a portal vein thrombosis. Because of several episodes of dyspnea, a pulmonary angiogram was also performed, and showed partial or complete obstruction of both inferior pulmonary arteries with "pruning" of lower lobes. Despite immediate anticoagulant therapy, the patient died suddenly some days later. We believe that oral contraceptive treatment could have induced thromboembolic disease both in portal and pulmonary circulations in this patient.

Citations

Apr 1, 1988·Baillière's Clinical Gastroenterology·D Valla, J P Benhamou
Mar 1, 1997·Contraception·P C HannafordJ Mant
Aug 23, 1986·Lancet·S Sherlock
Jul 15, 1999·Journal of Clinical Gastroenterology·H A Hassan
Jul 1, 1993·Journal of Gastroenterology and Hepatology·G Chu, G C Farrell
Oct 1, 1987·Gut·D R Triger
Jan 13, 2010·World Journal of Gastroenterology : WJG·Francesca R PonzianiAntonio Gasbarrini
Aug 22, 2015·Case Reports in Gastrointestinal Medicine·Bhradeev SivasambuThomas Wilson
Apr 2, 2002·The American Journal of Gastroenterology·Abhasnee Sobhonslidsuk, K Rajender Reddy
Dec 30, 2017·Khirurgiia·A I KhripunA D Pryamikov
Jan 29, 2008·Current Treatment Options in Gastroenterology·Hector Rodriguez-Luna, Hugo E Vargas

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