Portal vein thrombosis in a patient with Turner's syndrome: a case report

Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology
Soad A Shedeed

Abstract

This work aimed at reporting a case of Turner's syndrome with portal vein thrombosis and elevated levels of factor VIII and von Willebrand factor. A 14-year-old Libyan girl was admitted for evaluation of infantilism and pallor; meanwhile, she was found to be of short stature, with webbing of the neck. Chromosomal studies showed monosomy pattern Turner's syndrome (45XO). Abdominal ultrasound displayed a hugely enlarged spleen. Computed tomography (CT) imaging of the abdomen revealed portal vein thrombosis and dilated venous collaterals in porta hepatis. Thrombophilia screening demonstrated elevated levels of factor VIII (207 IU dl(-1)) and von Willebrand factor (450 IU dl(-1)). It was concluded that this was a case report on the unusual finding of portal vein thrombosis in a patient with Turner's syndrome in whom high levels of factor VIII and von Willebrand factor were found. Detailed molecular epidemiological study is recommended to clarify this finding and its underlying factors.

References

Aug 19, 2000·The New England Journal of Medicine·P A KyrleS Eichinger
Jun 1, 2006·Hormone Research·Cristiane Kopacek ZilzRegina Helena Elnecave
Jun 11, 2009·Clinical Endocrinology·Emma Jane Gault, Malcolm D C Donaldson

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Citations

Nov 19, 2015·Case Reports in Obstetrics and Gynecology·Nikolaos TsagkasTheodor Stefos
Sep 24, 2019·The Journal of Clinical Endocrinology and Metabolism·Mette H ViuffClaus H Gravholt

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