Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma: Diagnostic Accuracy of Gadoxetic Acid-enhanced MR Imaging

Radiology
Jae Hyun KimByung Ihn Choi

Abstract

Purpose To assess the diagnostic performance of gadoxetic acid-enhanced magnetic resonance (MR) imaging in the evaluation of portal vein thrombosis (PVT) in patients with hepatocellular carcinoma (HCC). Materials and Methods This retrospective study was approved by the institutional review board. The requirement to obtain informed consent was waived. A total of 366 patients with HCC who underwent gadoxetic acid-enhanced MR imaging between January 2007 and May 2013, including 134 with malignant PVT, 49 with benign PVT, and 183 without PVT matched for age and sex, comprised our study population. PVTs were complete in 125 patients and partial in 58 and were located in a major portal vein (n = 159) or segmental portal vein (n = 24). Two radiologists independently reviewed the MR images and assessed the sensitivity, specificity, and accuracy in the detection and characterization of PVT according to location (major vs segmental) and type (complete vs partial). The Fisher exact or χ(2) test was used to evaluate sensitivity difference between the subsets. Results Gadoxetic acid-enhanced MR imaging showed good sensitivity (reviewer 1, 84% [154 of 183 patients]; reviewer 2, 70% [129 of 183 patients]) and high specificity (reviewer 1, 89%...Continue Reading

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Citations

Sep 21, 2017·Abdominal Radiology·Scott M ThompsonSudhakar K Venkatesh
Sep 14, 2016·World Journal of Gastroenterology : WJG·Stephen L ChanKenneth S H Chok
Jun 14, 2019·Abdominal Radiology·Ryan B SchwopeChristopher J Lisanti
Nov 7, 2019·Abdominal Radiology·Guilherme M CunhaKathryn J Fowler
Jul 5, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jae Hyun KimJeong Min Lee
Oct 16, 2020·Insights Into Imaging·Ali Devrim KaraosmanogluMusturay Karcaaltincaba

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