Portal vein thrombosis successfully treated with a colectomy in active ulcerative colitis: report of a case

Diseases of the Colon and Rectum
T HagimotoT Iida

Abstract

Portal vein thrombosis is a rare complication in ulcerative colitis. We present a patient with portal vein thrombosis in ulcerative colitis who was successfully treated with colectomy. A 38-year-old Japanese female was admitted to our hospital because of an exacerbation of colitis. Abdominal ultrasonography performed because of liver dysfunction showed the thrombus in an umbilical portion of the portal vein. The patient underwent a subtotal colectomy and ileostomy because her colitis did not respond to intensive intravenous therapy. Although portal vein thrombus was treated with an intravenous infusion of urokinase before the operation, no change in the thrombus size was found. Approximately three months after the colectomy, the thrombus of the portal vein disappeared without anticoagulant therapy. Although a resection of an inflamed colon may be theoretically effective in the thrombosis in the inflammatory bowel disease, its benefit has not been confirmed. Our case suggests that the resection of the diseased bowel may have a favorable effect on the course of portal vein thrombosis in acute attacks of ulcerative colitis.

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Citations

Mar 13, 2009·Diseases of the Colon and Rectum·Francesco Di FabioPhilip H Gordon
May 13, 2008·Journal of Clinical Gastroenterology·Ibrahim ErtuğrulNurgül Saşmaz
Feb 7, 2013·Inflammatory Bowel Diseases·Cécilia LandmanUNKNOWN Groupe d'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif
Mar 13, 2012·Journal of Crohn's & Colitis·Giovanni MaconiRoberto de Franchis
Jun 1, 2011·Clinical Journal of Gastroenterology·Akitoshi KobayashiShoichi Matsutani
Mar 1, 2007·Journal of Ultrasound·D SacerdotiA Gatta
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Peter M IrvingDavid S Rampton
Apr 1, 2005·World Journal of Gastroenterology : WJG·Alfredo GuglielmiClaudio Cordiano

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