PMID: 3384371Jun 1, 1988Paper

Portal vein thrombosis with ruptured oesophageal varices as presenting manifestation of hereditary protein C deficiency

Gut
D VallaJ P Benhamou

Abstract

The protein C system is essential in limiting the activation of coagulation in vivo. We report the case of a 45 year old man with portal vein thrombosis complicated by ruptured oesophageal varices. Low concentration of plasma protein C was found in the patient and subsequently in one brother with a history of venous thromboembolism, and also in one son and one nephew who were asymptomatic. Hereditary protein C deficiency should be considered in patients with portal hypertension due to portal vein thrombosis.

References

Apr 1, 1975·Thrombosis Research·O R OdegardU Abildgaard
Feb 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·Y SakataD J Loskutoff
Dec 15, 1984·Thrombosis Research·C BoyerM J Larrieu
May 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D LebrecJ P Benhamou
Nov 10, 1984·British Medical Journal·M H HorellouM Samama
Aug 1, 1984·Thrombosis Research·U Abildgaard, M L Larsen
Aug 11, 1983·The New England Journal of Medicine·A W BroekmansR M Bertina
Jan 1, 1981·Annals of the New York Academy of Sciences·R A MarlarJ H Griffin
Nov 1, 1981·The Journal of Clinical Investigation·J H GriffinC Wideman
Apr 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·C T Esmon, W G Owen
Dec 26, 1964·Lancet·E N THOMPSONS SHERLOCK

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Citations

Jan 1, 1991·Gastrointestinal Radiology·D E BrinbergC Molin
Sep 29, 2005·Pediatric Surgery International·Tadao OkadaSatoru Todo
Jan 31, 1990·Clinica Chimica Acta; International Journal of Clinical Chemistry·P P Deutz-TerlouwR M Bertina
Mar 24, 1995·International Journal of Cardiology·M GalleraniS Moratelli
Jul 1, 1995·Trends in Cardiovascular Medicine·C T Esmon, H P Schwarz
Jul 1, 1997·Journal of Hepatology·C DubuissonO Bernard
Nov 26, 1999·Journal of Gastroenterology and Hepatology·Y Y YangS D Lee
May 1, 1991·Annals of Hematology·V De StefanoB Bizzi
Jun 1, 1997·The American Journal of Forensic Medicine and Pathology·J S Denton, B O Parks
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L AmitranoA Balzano
Apr 16, 2008·The American Journal of Emergency Medicine·Sundip N PatelMichael C Farmer
Jul 1, 1992·Current Problems in Diagnostic Radiology·P L Abbitt
Sep 1, 1993·Journal of Pediatric Surgery·H LaishramR Kennedy
Dec 31, 1998·Gastroenterology·P ChamouardP Oudet
Jul 18, 2000·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Y MiraJ Aznar
Jan 18, 2018·Journal of Translational Internal Medicine·Vania Cruz-RamónNahum Méndez-Sánchez

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