Portal vein thrombosis

The American Journal of Medicine
Sameer ParikhPrashant Kapoor

Abstract

Portal vein thrombosis is a condition not infrequently encountered by clinicians. It results from a combination of local and systemic prothrombotic risk factors. The presentation of acute thrombosis varies widely from an asymptomatic state to presence of life-threatening intestinal ischemia and infarction. In the chronic stage, patients typically present with variceal bleeding or other complications of portal hypertension. Abdominal ultrasound color Doppler imaging has a 98% negative predictive value, and is considered the imaging modality of choice in diagnosing portal vein thrombosis. Controlled clinical trials to assist with clinical decision-making are lacking in both acute and chronic portal vein thrombosis. Oral anticoagulant therapy is initiated if the risks of bleeding are low, but long-term anticoagulation is generally not recommended in patients with concomitant hepatic cirrhosis. The roles of invasive therapeutic approaches such as thrombolysis and transjugular intrahepatic portosystemic shunt continue to evolve. This review conflates dissenting views into a rational approach of managing patients with portal vein thrombosis for the general internist.

References

Jan 1, 1992·Gastrointestinal Radiology·M C HaddadB M Sammak
Mar 1, 1993·Archives of Surgery·P GertschL H Blumgart
Nov 1, 1996·American Journal of Surgery·N BarilS Stain
Jun 1, 1997·Journal of Clinical Ultrasound : JCU·N UenoK Kimura
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L AmitranoA Balzano
Jun 14, 2000·Journal of Hepatology·D C Valla, B Condat
Aug 5, 2000·QJM : Monthly Journal of the Association of Physicians·C L SheenJ K Ramage
Aug 29, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·B CondatD Valla
Nov 1, 2001·Journal of Gastroenterology and Hepatology·R ChandraS K Sarin
Dec 11, 2002·Journal of Gastroenterology and Hepatology·Dominique-Charles VallaDidier Lebrec
Dec 23, 2003·The American Journal of Gastroenterology·Lawrence Lai, William R Brugge
Apr 20, 2004·Journal of Hepatology·Lucio AmitranoAntonio Balzano
Apr 29, 2005·The New England Journal of Medicine·Robert KralovicsRadek C Skoda
May 6, 2005·Journal of Vascular and Interventional Radiology : JVIR·Michael HollingsheadPaul F Jaques
Jun 11, 2005·European Journal of Gastroenterology & Hepatology·A MangiaA Andriulli
Feb 24, 2006·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Ayman S AbdelrazeqStephen H Leveson
Jun 10, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Shiv Kumar SarinUNKNOWN Members of the APASL Working Party on Portal Hypertension
Nov 30, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Massimo PrimignaniPier Mannuccio Mannucci
Dec 5, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·David W OrrMichael A Heneghan
Jun 26, 2007·Cardiovascular and Interventional Radiology·Aslihan Semiz-OysuWojciech Cwikiel
Jun 27, 2007·Annals of Surgery·Eric VibertDenis Castaing
Aug 19, 2007·BMC Gastroenterology·Kirstine K SogaardHenning Gronbaek
Oct 26, 2007·The American Journal of Gastroenterology·Lucio AmitranoAntonio Balzano
Feb 16, 2008·Internal and Emergency Medicine·Filippo Luca Fimognari, Francesco Violi

❮ Previous
Next ❯

Citations

Nov 19, 2011·Annals of Hematology·Jecko ThachilAnita Hill
Aug 7, 2012·Interface Focus·David H EvansMichael Bachmann Nielsen
Nov 17, 2012·World Journal of Gastroenterology : WJG·Won-Seok ParkSeung-Ok Lee
Mar 15, 2013·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Jacob M RosenbergDan Eisenberg
Sep 12, 2012·World Journal of Surgery·David AnsariRalf Segersvärd
May 30, 2015·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Junna DaiXiaozhong Guo
Apr 23, 2016·Gastroenterology Report·Yashwant PatidarRakhi Maiwall
May 26, 2016·Internal and Emergency Medicine·Stefano LancellottiRaimondo De Cristofaro
Jul 20, 2016·Oxidative Medicine and Cellular Longevity·Meng XuShengli Wu
Dec 8, 2015·Case Reports in Gastrointestinal Medicine·Murad BabaAmer Syed
Sep 5, 2014·BMJ Case Reports·Lennard Y W LeeAminda De Silva
Aug 5, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Noriaki NaeshiroKazuaki Chayama
Feb 1, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Pankaj HandaJames D Douketis
Dec 21, 2017·Case Reports in Hepatology·Igor DumicTamara Alempijevic
May 25, 2018·AJR. American Journal of Roentgenology·Reena C JhaAmit Dinesh Kalaria
Feb 10, 2012·Journal of Veterinary Emergency and Critical Care·Carrie KavanaghCynthia R L Webster
May 24, 2016·Korean Journal of Hepato-biliary-pancreatic Surgery·Sung Hyun KimKyung Sik Kim
May 23, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Su Jin ChoiYoung Ok Kim
Jun 18, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Yoon Gwon MunByeong Seong Ko
Jan 24, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Myung Jo KimSung-Bum Kang
Apr 2, 2014·Nature Reviews. Gastroenterology & Hepatology·Xingshun QiDaiming Fan
Oct 3, 2019·Pediatrics in Review·Soham DasguptaAndrea M Glaser
Jul 12, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Seth A WaitsMichael J Englesbe
Aug 14, 2012·British Journal of Haematology·Campbell TaitUNKNOWN British Committee for Standards in Haematology
Aug 31, 2012·Journal of Orthopaedic Surgery·Guy MartinSimon Jennings
Dec 4, 2014·World Journal of Gastroenterology : WJG·Wei JiangJie-Shou Li
Apr 4, 2017·Abdominal Radiology·Yonah B EstersonGregory M Grimaldi
Feb 28, 2019·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Jong Do SeoHyun Kyung Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Ryan M Thomas, Syed A Ahmad
Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
M Primignani
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
M H DenningerD Valla
© 2021 Meta ULC. All rights reserved