Portrait of an immunoregulatory Bifidobacterium.

Gut Microbes
Patrycja KoniecznaLiam O'Mahony

Abstract

There is increasing interest in the administration of microbes or microbial metabolites for the prevention and treatment of aberrant inflammatory activity. The protective effects associated with these microbes are mediated by multiple mechanisms involving epithelial cells, DCs and T cells, but most data are derived from animal models. In this addendum, we summarize our recent data, showing that oral consumption of Bifidobacterium infantis 35624 is associated with enhanced IL-10 secretion and Foxp3 expression in human peripheral blood. In addition, we discuss the potential DC subset-specific mechanisms, which could contribute to DC(REG) and T(REG) programming by specific gut microbes.

References

Jun 3, 2000·Annual Review of Immunology·J BanchereauK Palucka
Jan 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mahzuz KarimKathryn J Wood
Mar 24, 2005·Nature Immunology·Yasmine Belkaid, Barry T Rouse
Nov 19, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·Liam O'MahonyFergus Shanahan
Jul 5, 2006·EMBO Reports·Ann M O'Hara, Fergus Shanahan
Jul 26, 2006·The American Journal of Gastroenterology·Peter J WhorwellEamonn M M Quigley
Jul 11, 2007·The Journal of Experimental Medicine·Cheng-Ming SunYasmine Belkaid
Aug 1, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Hanneke van der KleijJohn Bienenstock
Aug 30, 2008·Scandinavian Journal of Gastroenterology·John MacsharryEamonn M M Quigley
Oct 16, 2009·Current Opinion in Pharmacology·Masayuki Fukata, Maria T Abreu
Jan 14, 2010·The American Journal of Gastroenterology·Fergus Shanahan
Mar 3, 2010·Immunological Reviews·John R GraingerYasmine Belkaid
Mar 23, 2010·Cell·Dan R Littman, Alexander Y Rudensky
Apr 22, 2010·The American Journal of Gastroenterology·Paul ScullyEamonn M M Quigley
Jun 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·June L Round, Sarkis K Mazmanian
Oct 15, 2010·Mucosal Immunology·T Feng, C O Elson
Dec 21, 2010·Nature Immunology·Kendle M Maslowski, Charles R Mackay
Mar 8, 2011·The Journal of Allergy and Clinical Immunology·Mübeccel AkdisCezmi A Akdis

❮ Previous
Next ❯

Citations

Nov 28, 2013·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Rachel D MoloneyJohn F Cryan
Oct 14, 2014·Autoimmunity Reviews·Mitesh DwivediRasheedunnisa Begum
Jan 5, 2013·Current Opinion in Gastroenterology·Kevin Whelan, Eamonn M M Quigley
Feb 13, 2013·Current Opinion in Allergy and Clinical Immunology·Susanne Lau
Oct 30, 2012·Gastroenterology Clinics of North America·Eamonn M M Quigley
Dec 5, 2015·Frontiers in Immunology·Borja SánchezAbelardo Margolles
Aug 16, 2014·Journal of Digestive Diseases·Rong LinXiao Hua Hou
Jul 12, 2013·Gut Microbes·David GroegerEamonn M M Quigley
Jun 24, 2014·The Journal of Allergy and Clinical Immunology·Ruth FerstlLiam O'Mahony
May 14, 2016·Clinical and Translational Allergy·Bodo C MelnikGerd Schmitz
Aug 9, 2016·International Journal of Biological Macromolecules·Mariano Prado AcostaSandra M Cordo
Nov 25, 2016·Molecular Nutrition & Food Research·Amel TaibiElena M Comelli
Nov 10, 2015·The British Journal of Nutrition·Linda V ThomasJia Zhao
Apr 25, 2018·Journal of Neurogastroenterology and Motility·Fanny Giron, Eamonn M M Quigley
Sep 21, 2018·The Australian and New Zealand Journal of Psychiatry·Gerwyn MorrisMichael Berk
Aug 24, 2018·Pediatric Diabetes·Richard Insel, Mikael Knip
Oct 24, 2018·Molecular Microbiology·Mary O'Connell MotherwayFergus Shanahan
Jul 30, 2014·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Bodo C Melnik
Oct 30, 2019·British Journal of Pharmacology·Eamonn M M Quigley
Dec 3, 2016·Probiotics and Antimicrobial Proteins·Eric Banan-Mwine DaliriDeog H Oh
Jan 29, 2019·Frontiers in Pharmacology·Paulo José BassoHelioswilton Sales-Campos
Jan 18, 2018·Annals of the New York Academy of Sciences·Elena RinaldiFulvio Baggi
Sep 12, 2019·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Gerwyn MorrisMichael Berk
Jan 22, 2021·Autoimmunity Reviews·Zhussipbek MukhatayevI Caroline Le Poole
Sep 20, 2017·Current Opinion in Immunology·Weronika BarcikLiam O'Mahony
Aug 8, 2021·International Journal of Molecular Sciences·Shaghayegh Baradaran GhavamiMohammad Reza Zali
Sep 14, 2021·The British Journal of Nutrition·Mostafa Hassan BakyMohamed A Farag

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.