Posey and Spiller and progressive supranuclear palsy: an incorrect attribution

Movement Disorders : Official Journal of the Movement Disorder Society
A D SiderowfG T Liu

Abstract

In 1904 and 1905, respectively, William Campbell Posey and William Spiller both described the case of a patient with progressive ophthalmoparesis and imbalance that has come to be regarded as the earliest report of progressive supranuclear palsy. No autopsy was thought to have been performed on this patient. In this report, we review the clinical history provided by Posey and Spiller. We also report on the subsequent autopsy of their patient, which was performed by Spiller in 1906. The chief finding was a tumor involving the right cerebral peduncle and periaqueductal area. The autopsy findings prove conclusively that the patient described by Spiller and Posey had a midbrain neoplasm and not progressive supranuclear palsy.

Citations

Aug 6, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·C N HomannH P Hartung
Jan 25, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·A J MansonA J Lees
Apr 20, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Jan LewerenzAlexander Münchau
Aug 10, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Paul H GordonDavid Eidelberg
Jul 18, 2008·Handbook of Clinical Neurology·Shaheda N Azher, Joseph Jankovic
Mar 17, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Adolfo BrusaPeter P Pramstaller
Aug 11, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Tomaso ScaravilliIsidre Ferrer
Mar 16, 2002·Journal of Neuropathology and Experimental Neurology·Roberta VitalianiPeter P Pramstaller
Sep 8, 2017·Frontiers in Neurology·Alexandra Lloyd-Smith SequeiraJanet C Rucker

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